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Descriptor in English: Muscimol
Descriptor in Spanish: Muscimol
Descriptor in Portuguese: Muscimol
Descriptor in French: Muscimol
Entry term(s): Agarin
Pantherine
Tree number(s): D03.383.129.462.470
D23.946.587.587
Scope note: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 86(79); was see under OXAZOLES 1979-85
See also the descriptors: Receptors, GABA-A MeSH
DeCS UI: 9308
Descriptor UI: D009118
Date Established: 1986/01/01
Date of Entry: 1978/05/03
Revision Date: 2016/05/31
Muscimol - Preferred
Concept UI M0014231
Scope note A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Preferred term Muscimol
Entry term(s) Agarin
Pantherine



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