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Descriptor English: Nicotine
Descriptor Spanish: Nicotina
Descriptor nicotina
Scope note: La nicotina es un alcaloide altamente tóxico. Es el agonista prototípico de los receptores nicotínicos colinérgicos, actuando estimulando intensamente las neuronas y, finalmente, bloqueando la transmisión sináptica. La nicotina también es importante desde el punto de vista médico debido a su presencia en el humo del tabaco.
Descriptor Portuguese: Nicotina
Descriptor French: Nicotine
Entry term(s): Bitartrate de nicotine
Tree number(s): D03.132.760.570
D03.383.725.518
SP4.606.806.945.200.606.581
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009538
Scope note: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Smoking Cessation Agents
Ganglionic Stimulants
Nicotinic Agonists
Registry Number: 6M3C89ZY6R
CAS Type 1 Name: Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-
DeCS ID: 9723
Unique ID: D009538
NLM Classification: QV 137
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/04/10
Nicotine - Preferred
Concept UI M0014836
Preferred term Nicotine
Bitartrate de nicotine - Narrower
Concept UI M0014837
Preferred term Bitartrate de nicotine



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