Visão selecionada em Inglês
| Descritor em português: | Ataxinas | ||||||
| Descritor em inglês: | Ataxins | ||||||
| Descritor em espanhol: |
Ataxinas
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| Descritor em francês: | Ataxines | ||||||
| Termo(s) alternativo(s): |
Ataxia Protein, Spinocerebellar Ataxia Proteins, Spinocerebellar Ataxin Ataxin Protein Ataxin Proteins Protein, Ataxin Protein, Spinocerebellar Ataxia Proteins, Ataxin Proteins, Spinocerebellar Ataxia Spinocerebellar Ataxia Protein Spinocerebellar Ataxia Proteins |
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| Código(s) hierárquico(s): |
D12.776.631.069 D12.776.660.075 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000067528 | ||||||
| Nota de escopo: | A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Indexação Anterior: |
Nerve Tissue Proteins (1995-2015) Nuclear Proteins (1995-2015) |
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| Nota MeSH pública: | 2016 |
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| Nota histórica: | 2016 |
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| Veja também os descritores: |
Spinocerebellar Ataxias
MeSH | ||||||
| Identificador DeCS: | 56001 | ||||||
| ID do descritor: | D000067528 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/2016 | ||||||
| Data de entrada: | 06/07/2015 | ||||||
| Data de revisão: | 27/05/2020 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Ataxins
- Conceito preferido
| Identificador do conceito |
M000599991 |
| Nota de escopo | A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset. |
| Termo preferido | Ataxins |
| Termo(s) alternativo(s) |
Ataxia Protein, Spinocerebellar Ataxia Proteins, Spinocerebellar Ataxin Ataxin Protein Ataxin Proteins Protein, Ataxin Protein, Spinocerebellar Ataxia Proteins, Ataxin Proteins, Spinocerebellar Ataxia Spinocerebellar Ataxia Protein Spinocerebellar Ataxia Proteins |
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