| Descriptor English: | Pyrrolizidine Alkaloids | ||||||
| Descriptor Spanish: |
Alcaloides de Pirrolicidina
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| Descriptor Portuguese: | Alcaloides de Pirrolizidina | ||||||
| Descriptor French: | Alcaloïdes de type pyrrolizidine | ||||||
| Entry term(s): |
Alkaloid, Pyrrolizidine Alkaloid, Senecio Alkaloids, Pyrrolizidine Alkaloids, Senecio Pyrrolizidine Alkaloid Senecio Alkaloid Senecio Alkaloids |
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| Tree number(s): |
D03.132.716 D03.633.100.772 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011763 | ||||||
| Scope note: | A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Previous Indexing: |
Alkaloids (1966-1970) Heterocyclic Compounds (1966-1970) |
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| Public MeSH Note: | 73 |
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| History Note: | 73(71) |
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| DeCS ID: | 12200 | ||||||
| Unique ID: | D011763 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1973/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Pyrrolizidine Alkaloids
- Preferred
Senecio Alkaloids
- Related but not broader or narrower
| Concept UI |
M0018283 |
| Scope note | A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS. |
| Preferred term | Pyrrolizidine Alkaloids |
| Entry term(s) |
Alkaloid, Pyrrolizidine Alkaloids, Pyrrolizidine Pyrrolizidine Alkaloid |
| Concept UI |
M0018284 |
| Preferred term | Senecio Alkaloids |
| Entry term(s) |
Alkaloid, Senecio Alkaloids, Senecio Senecio Alkaloid |
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