DeCS

Descriptor English:

Veratrum Alkaloids

Descriptor Spanish:

Alcaloides de Veratrum

Spanish from Spain

Descriptor

alcaloides de veratrum

Scope note:

Alcaloides con potentes efectos hipotensores, aislados de la Hellebore americana o europea (Veratrum viride Ait. Liliaceae y Veratrum album L. Liliaceae). Aumentan y disminuyen el tono adrenérgico con los consiguientes efectos secundarios y, a dosis mayores, deprimen la respiración y producen arritmias cardíacas; solamente han sido utilizados como agentes hipotensores en situaciones específicas. Generalmente han sido sustituidos por drogas con menos efectos secundarios.

Descriptor Portuguese:

Alcaloides de Veratrum

Descriptor French:

Alcaloïdes de Veratrum

Tree number(s):

D03.132.920

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D014704

Scope note:

Alkaloids with powerful hypotensive effects isolated from American or European Hellebore (Veratrum viride Ait. Liliaceae and Veratrum album L. Liliaceae). They increase cholinergic and decrease adrenergic tone with appropriate side effects and at higher doses depress respiration and produce cardiac arrhythmias; only the ester alkaloids have been used as hypotensive agents in specific instances. They have been generally replaced by drugs with fewer adverse effects.

Annotation:

antihypertensives

Allowable Qualifiers:

AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antihypertensive Agents

DeCS ID:

15109

Unique ID:

D014704

NLM Classification:

QV 151

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

1975/01/01