Search
Descriptor English: DNA, Satellite
Descriptor Spanish: ADN Satélite
Descriptor ADN satélite
Scope note: Secuencias altamente repetitivas de ADN que se encuentran en la HETEROCROMATINA, fundamentalmente cerca de los centrómeros. Están compuestos por secuencias simples (muy cortas) (ver REPETICIONES MINISATÉLITES) repetidas de una en una y muchas veces para formar grandes bloques de secuencias. Adicionalmente, tras la acumulación de mutaciones, estos bloques de repeticiones han sido repetidos ellos mismos en línea. El grado de repetición es del orden de 1000 a 10 millones en cada locus. Los loci son pocos, generalmente uno o dos por cromosoma. Se los denominó satélites ya que en gradientes de densidad, a menudo sedimentan como bandas satélite distintas separadas del grueso del ADN del genoma debido a su diferente COMPOSICIÓN DE BASES.
Descriptor Portuguese: DNA Satélite
Descriptor French: ADN satellite
Entry term(s): ADN satellite I
Tree number(s): D13.444.308.480
G02.111.570.080.708.800.150
G05.360.080.708.800.150
G05.360.340.024.220.150
G05.360.340.024.850.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004276
Scope note: Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Related: Centromère MeSH
DeCS ID: 22160
Unique ID: D004276
NLM Classification: QU 58.5
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2008/07/08
ADN satellite - Preferred
Concept UI M0006691
Preferred term ADN satellite
ADN satellite I - Narrower
Concept UI M0006692
Preferred term ADN satellite I



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey