DeCS

Descriptor English:

CD4 Antigens

Descriptor Spanish:

Antígenos CD4

Spanish from Spain

Descriptor	antígenos CD4
Entry term(s)	CD4 antígeno CD4 antígenos T4 de células-T antígenos T4 de los linfocitos T molécula CD4 receptor CD4 receptor CD4 de superficie receptor CD4 de superficie de células T receptor de superficie CD4 receptor de superficie CD4 de los linfocitos T receptores CD4 receptores CD4 de superficie receptores CD4 de superficie de células T receptores de superficie CD4 receptores de superficie CD4 de los linfocitos T
Scope note:	Antígenos de 55-kDa que se encuentran en los LINFOCITOS T AUXILIARES-INDUCTORES y en diversos tipos de células del sistema inmunitario. Los antígenos CD4 son miembros de la familia de supergenes de inmunoglobulinas y están implicados, como elementos de reconocimiento asociativo, en el COMPLEJO PRINCIPAL DE HISTOCOMPATIBILIDAD en las respuestas inmunológicas de clase II. En los linfocitos-T definen el subconjunto favorecedor/inductor. Los antígenos CD4 también actúan como receptores de INTERLEUCINA-15 y se unen a los receptores del VIH, acoplándose directamente a la PROTEÍNA DE CUBIERTA GP120 DEL VIH.

Descriptor Portuguese:

Antígenos CD4

Descriptor French:

Antigènes CD4

Entry term(s):

Antigen, CD4
Antigens, CD4
Antigens, T-Cell T4
CD4 Antigen
CD4 Molecule
CD4 Receptor
CD4 Receptor, Surface
CD4 Receptors
CD4 Receptors, Surface
Receptors, CD4
Receptors, Surface CD4
Surface CD4 Receptor
Surface CD4 Receptors
T-Cell T4 Antigens
T4 Antigens, T Cell
T4 Antigens, T-Cell

Tree number(s):

D12.776.543.750.705.852.420.810.500
D12.776.543.750.830.700.025
D23.050.301.264.894.100
D23.101.100.894.100

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D015704

Scope note:

55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.

Annotation:

for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN

Allowable Qualifiers:

AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure

Concept UI	M0024088
Scope note	55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
Preferred term	CD4 Antigens
Entry term(s)	Antigen, CD4 Antigens, CD4 Antigens, T-Cell T4 CD4 Antigen CD4 Molecule CD4 Receptor CD4 Receptor, Surface CD4 Receptors CD4 Receptors, Surface Receptors, CD4 Receptors, Surface CD4 Surface CD4 Receptor Surface CD4 Receptors T-Cell T4 Antigens T4 Antigens, T Cell T4 Antigens, T-Cell

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