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Descriptor English: Programmed Cell Death 1 Receptor
Descriptor Spanish: Receptor de Muerte Celular Programada 1
Descriptor receptor 1 de la muerte celular programada
Entry term(s) proteína 1 de la muerte celular programada
proteína PD-1
proteína de muerte celular programada 1
receptor PD-1
receptor de la muerte celular programada 1
Scope note: Un receptor inhibidor de linfocitos T que tiene una especificidad de ANTÍGENO CD274 y MUERTE CELULAR PROGRAMADA AL LIGANDO1 PROTEINA 2. Señalización por el receptor limita la proliferación de células T y la síntesis del INTERFERON GAMMA. El receptor también puede desempeñar un papel esencial en la vía de reglamentación que induce la TOLERANCIA PERIFÉRICA.
Descriptor Portuguese: Receptor de Morte Celular Programada 1
Descriptor French: Récepteur-1 de mort cellulaire programmée
Entry term(s): Antigen, CD279
Antigens, CD279
CD279 Antigen
CD279 Antigens
PD 1 Protein
PD 1 Receptor
PD-1 Protein
PD-1 Receptor
PD1 Receptor
Programmed Cell Death 1 Protein
Programmed Cell Death Protein 1
Receptor, PD-1
Receptor, PD1
Tree number(s): D12.776.465.844
D12.776.543.750.705.222.875
D23.050.301.264.894.790
D23.101.100.894.790
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D061026
Scope note: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Antigens, CD (1997-2011)
Antigens, Surface (1997-2006)
Apoptosis Regulatory Proteins (1977-2011)
Public MeSH Note: 2012
History Note: 2012
Related: Immunoglobulin Domains MeSH
DeCS ID: 54636
Unique ID: D061026
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2020/03/27
Programmed Cell Death 1 Receptor - Preferred
Concept UI M0556121
Scope note An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
Preferred term Programmed Cell Death 1 Receptor
Entry term(s) Antigen, CD279
Antigens, CD279
CD279 Antigen
CD279 Antigens
PD 1 Protein
PD 1 Receptor
PD-1 Protein
PD-1 Receptor
PD1 Receptor
Programmed Cell Death 1 Protein
Programmed Cell Death Protein 1
Receptor, PD-1
Receptor, PD1



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