| Descriptor English: | Oncogene Protein p21(ras) | ||||||
| Descriptor Spanish: |
Proteína Oncogénica p21(ras)
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| Descriptor Portuguese: | Proteína Oncogênica p21(ras) | ||||||
| Descriptor French: | Protéine oncogène p21(ras) | ||||||
| Entry term(s): |
p21 Transforming Viral Protein p21 v H ras p21 v Ha ras p21 v Ki ras p21 v ras p21 v-H-ras p21 v-Ha-ras p21 v-Ki-ras p21 v-ras p21(v-H-ras) p21(v-Ha-ras) p21(v-K-ras) p21(v-Ki-ras) ras Oncogene Product p21 ras Oncogene Protein p21 ras Oncogene p21 Product v-H-ras, p21 v-Ha-ras, p21 v-Ki-ras, p21 v-ras, p21 |
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| Tree number(s): |
D08.811.277.040.330.300.400.500.300 D12.776.157.325.515.500.300 D12.776.476.338.400.500.300 D12.776.624.664.520.750.710 D12.776.964.700.750.710 D12.776.964.775.750.710 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015689 | ||||||
| Scope note: | Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47. |
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| Annotation: | coord with specific virus |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.6.5.2 | ||||||
| Previous Indexing: |
Neoplasm Proteins (1980-1986) Oncogene Proteins, Viral (1986-1989) |
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| Public MeSH Note: | 1990 |
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| History Note: | 1990 |
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| DeCS ID: | 24815 | ||||||
| Unique ID: | D015689 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1990/01/01 | ||||||
| Date of Entry: | 1989/07/19 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Oncogene Protein p21(ras)
- Preferred
| Concept UI |
M0024065 |
| Scope note | Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47. |
| Preferred term | Oncogene Protein p21(ras) |
| Entry term(s) |
p21 Transforming Viral Protein p21 v H ras p21 v Ha ras p21 v Ki ras p21 v ras p21 v-H-ras p21 v-Ha-ras p21 v-Ki-ras p21 v-ras p21(v-H-ras) p21(v-Ha-ras) p21(v-K-ras) p21(v-Ki-ras) ras Oncogene Product p21 ras Oncogene Protein p21 ras Oncogene p21 Product v-H-ras, p21 v-Ha-ras, p21 v-Ki-ras, p21 v-ras, p21 |
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