| Descriptor English: | Oncogene Protein pp60(v-src) | ||||||
| Descriptor Spanish: |
Proteína Oncogénica pp60(v-src)
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| Descriptor Portuguese: | Proteína Oncogênica pp60(v-src) | ||||||
| Descriptor French: | Protéine oncogène pp60(v-src) | ||||||
| Entry term(s): |
Avian Sarcoma Virus Transforming Protein Avian Sarcoma Virus-Transforming Protein Oncogene Protein pp60(src) Oncogene Protein src Phosphoprotein pp60(v-src) Protein pp60, v-src Protein src, Oncogene Rous Sarcoma Virus-Transforming Protein pp60(v-src) p60(v-src) pp60 v src pp60 v-src pp60(v-src) pp60, v-src Protein src Oncogene Product pp60 src Oncogene Protein pp60 src, Oncogene Protein v src Protein v src Protein pp60 v-src Protein v-src Protein pp60 v-src, pp60 |
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| Tree number(s): |
D08.811.913.696.620.682.725.800.472 D12.776.476.568.800.472 D12.776.624.664.520.750.760 D12.776.964.700.750.760 D12.776.964.775.750.760 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015688 | ||||||
| Scope note: | A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.10.2 | ||||||
| CAS Type 1 Name: | Kinase (phosphorylating), protein pp60src | ||||||
| Previous Indexing: |
Retroviridae Proteins (1986-1989) Viral Proteins (1981-1985) |
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| Public MeSH Note: | 91; was ONCOGENE PROTEIN PP60(SRC) 1990; PP60(SRC) was see ONCOGENE PROTEIN PP60(SRC) 1990 |
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| Online Note: | use ONCOGENE PROTEIN PP60(V-SRC) to search ONCOGENE PROTEIN PP60(SRC) & PP60(SRC) 1990 |
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| History Note: | 91; was ONCOGENE PROTEIN PP60(SRC) 1990; PP60(SRC) was see ONCOGENE PROTEIN PP60(SRC) 1990 |
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| DeCS ID: | 29308 | ||||||
| Unique ID: | D015688 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1990/01/01 | ||||||
| Date of Entry: | 1989/05/25 | ||||||
| Revision Date: | 2009/07/06 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Oncogene Protein pp60(v-src)
- Preferred
| Concept UI |
M0024064 |
| Scope note | A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine. |
| Preferred term | Oncogene Protein pp60(v-src) |
| Entry term(s) |
Avian Sarcoma Virus Transforming Protein Avian Sarcoma Virus-Transforming Protein Oncogene Protein pp60(src) Oncogene Protein src Phosphoprotein pp60(v-src) Protein pp60, v-src Protein src, Oncogene Rous Sarcoma Virus-Transforming Protein pp60(v-src) p60(v-src) pp60 v src pp60 v-src pp60(v-src) pp60, v-src Protein src Oncogene Product pp60 src Oncogene Protein pp60 src, Oncogene Protein v src Protein v src Protein pp60 v-src Protein v-src Protein pp60 v-src, pp60 |
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