| Descriptor English: | Proto-Oncogene Proteins p21(ras) | ||||||
| Descriptor Spanish: |
Proteínas Proto-Oncogénicas p21(ras)
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| Descriptor Portuguese: | Proteínas Proto-Oncogênicas p21(ras) | ||||||
| Descriptor French: | Protéines proto-oncogènes p21(ras) | ||||||
| Entry term(s): |
Proteins c-ras, Proto-Oncogene Proto Oncogene Protein ras Proto Oncogene Proteins c ras Proto-Oncogene Protein p21(c-Ha-ras) Proto-Oncogene Protein p21(c-Ki-ras) Proto-Oncogene Protein p21(c-N-ras) Proto-Oncogene Protein p21(ras) Proto-Oncogene Protein ras Proto-Oncogene Proteins c-ras c Ha ras p21 c Ki ras p21 c ras Proteins c-H-ras, p21 c-Ha-ras p21 c-Ha-ras, p21 c-K-ras, p21 c-Ki-ras p21 c-Ki-ras, p21 c-ras Proteins c-ras, Proto-Oncogene Proteins c-ras, p21 p21 c H ras p21 c Ha ras p21 c K ras p21 c Ki ras p21 c ras p21 c-H-ras p21 c-Ha-ras p21 c-K-ras p21 c-Ki-ras p21 c-ras p21(N-ras) p21(c-Ha-ras) p21(c-Ki-ras) p21(c-ras) p21(ras) p21, c-Ha-ras p21, c-Ki-ras ras Proto Oncogene Product p21 ras Proto Oncogene Protein p21 ras Proto-Oncogene Product p21 ras Proto-Oncogene Protein p21 ras, Proto-Oncogene Protein |
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| Tree number(s): |
D08.811.277.040.330.300.400.500.600 D12.776.157.325.515.500.600 D12.776.476.338.400.500.600 D12.776.624.664.700.200 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016283 | ||||||
| Scope note: | Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric GTP-binding proteins. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.6.5.2 | ||||||
| Previous Indexing: |
Neoplasm Proteins (1983-1986) Proto-Oncogene Proteins (1987-1990) |
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| Public MeSH Note: | 2006; for P21(RAS) see ONCOGENE PROTEIN P21(RAS) 1990 |
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| History Note: | 2006(1991) |
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| Related: |
Costello Syndrome
MeSH | ||||||
| DeCS ID: | 29090 | ||||||
| Unique ID: | D016283 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1990/06/19 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Proto-Oncogene Proteins p21(ras)
- Preferred
Proto-Oncogene Protein p21(c-N-ras)
- Narrower
Proto-Oncogene Protein p21(c-Ha-ras)
- Narrower
Proto-Oncogene Protein p21(c-Ki-ras)
- Narrower
| Concept UI |
M0024891 |
| Scope note | Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric GTP-binding proteins. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47. |
| Preferred term | Proto-Oncogene Proteins p21(ras) |
| Entry term(s) |
Proteins c-ras, Proto-Oncogene Proto Oncogene Protein ras Proto Oncogene Proteins c ras Proto-Oncogene Protein p21(ras) Proto-Oncogene Protein ras Proto-Oncogene Proteins c-ras c ras Proteins c-ras Proteins c-ras, Proto-Oncogene Proteins c-ras, p21 p21 c ras p21 c-ras p21(c-ras) p21(ras) ras Proto Oncogene Product p21 ras Proto Oncogene Protein p21 ras Proto-Oncogene Product p21 ras Proto-Oncogene Protein p21 ras, Proto-Oncogene Protein |
| Concept UI |
M0024890 |
| Preferred term | Proto-Oncogene Protein p21(c-N-ras) |
| Entry term(s) |
p21(N-ras) |
| Concept UI |
M0024888 |
| Preferred term | Proto-Oncogene Protein p21(c-Ha-ras) |
| Entry term(s) |
c Ha ras p21 c-H-ras, p21 c-Ha-ras p21 c-Ha-ras, p21 p21 c H ras p21 c Ha ras p21 c-H-ras p21 c-Ha-ras p21(c-Ha-ras) p21, c-Ha-ras |
| Concept UI |
M0024889 |
| Preferred term | Proto-Oncogene Protein p21(c-Ki-ras) |
| Entry term(s) |
c Ki ras p21 c-K-ras, p21 c-Ki-ras p21 c-Ki-ras, p21 p21 c K ras p21 c Ki ras p21 c-K-ras p21 c-Ki-ras p21(c-Ki-ras) p21, c-Ki-ras |
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