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Descriptor English: Antithrombin III
Descriptor Spanish: Antitrombina III
Descriptor antitrombina III
Entry term(s) cofactor I de heparina
Scope note: Glicoproteína alfa 2 plasmática que da cuenta de la mayor parte de la actividad antitrombínica del plasma normal e inhibe también otras varias enzimas; fue denominada antiguamente Antitrombina II (AT II) que, según se ha demostrado ahora, es idéntica a la AT III; La DEFICIENCIA EN ANTITROMBINA III, hereditaria o adquirida, da lugar a tromboembolias. Es miembro de la superfamilia de las serpinas. Algunos autores utilizan el término antitrombina para referirse a la antitrombina III.
Descriptor Portuguese: Antitrombina III
Descriptor French: Antithrombine-III
Entry term(s): Antithrombin III Alpha
Antithrombin III-Alpha
Antithrombin IIIAlpha
Atenativ
Cofactor I, Heparin
Heparin Co Factor I
Heparin Co-Factor I
Heparin Cofactor I
Kybernin
Serpin C1
Thrombate III
Tree number(s): D12.644.861.060.500
D12.776.124.790.106.125
D12.776.377.715.085.125
D12.776.872.060.500
D23.113.025
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000990
Scope note: A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Antithrombin III Deficiency
Pharm Action: Antithrombins
Registry Number: 9000-94-6
Public MeSH Note: 1979; see HEPARIN CO-FACTOR 1975-1978; KYBERNIN was indexed under ANTITHROMBIN III 1992-2010
History Note: 1979
DeCS ID: 27942
Unique ID: D000990
NLM Classification: QV 193
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1979/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
Antithrombin III - Preferred
Concept UI M0001509
Scope note A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Preferred term Antithrombin III
Entry term(s) Cofactor I, Heparin
Heparin Co Factor I
Heparin Co-Factor I
Heparin Cofactor I
Serpin C1
Atenativ - Narrower
Concept UI M0434012
Preferred term Atenativ
Thrombate III - Narrower
Concept UI M0434014
Preferred term Thrombate III
Antithrombin III-Alpha - Narrower
Concept UI M0434010
Preferred term Antithrombin III-Alpha
Entry term(s) Antithrombin III Alpha
Antithrombin IIIAlpha
Kybernin - Narrower
Concept UI M0200269
Preferred term Kybernin



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