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Descriptor English: alpha-2-Antiplasmin
Descriptor Spanish: alfa 2-Antiplasmina
Descriptor alfa 2-antiplasmina
Entry term(s) inhibidor de plasmina alfa-2
Scope note: Miembro de la superfamilia de serpinas observado en el plasma que inhibe la lisis de los coágulos de fibrina inducidos por el activador del plasminógeno. Es una glicoproteína, de peso molecular de aproximadamente 70.000 que migra en la región alfa 2 en la inmunoelectroforesis. Es el principal inactivador de plasmina en la sangre, formando rápidamente un complejo muy estable con la plasmina.
Descriptor Portuguese: alfa 2-Antiplasmina
Descriptor French: alpha-2-Antiplasmine
Entry term(s): Serpin F2
alpha 2 Antiplasmin
alpha 2 Plasmin Inhibitor
alpha 2-Plasmin Inhibitor
alpha(2)-Plasmin Inhibitor
alpha-2 Antiplasmin
Tree number(s): D12.644.861.050
D12.776.124.790.106.090
D12.776.377.715.085.090
D12.776.395.080
D12.776.872.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000979
Scope note: A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Antifibrinolytic Agents
Serine Proteinase Inhibitors
Previous Indexing: Fibrinolysin/antagonists & inhibitors (1968-1979)
Public MeSH Note: 2010; see ANTIPLASMIN 1980-2009
History Note: 2010(1980)
DeCS ID: 28329
Unique ID: D000979
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1979/05/23
Revision Date: 2015/06/23
alpha-2-Antiplasmin - Preferred
Concept UI M0001495
Scope note A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.
Preferred term alpha-2-Antiplasmin
Entry term(s) Serpin F2
alpha 2 Antiplasmin
alpha 2 Plasmin Inhibitor
alpha 2-Plasmin Inhibitor
alpha(2)-Plasmin Inhibitor
alpha-2 Antiplasmin



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