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Descriptor English: Protein S
Descriptor Spanish: Proteína S
Descriptor Portuguese: Proteína S
Descriptor French: Protéine S
Entry term(s): Cofactor Protein S
Protein S, Cofactor
Protein S, Vitamin K Dependent
Protein S, Vitamin K-Dependent
Vitamin K Dependent Protein S
Vitamin K-Dependent Protein S
Tree number(s): D12.776.124.670
D12.776.395.642
D23.113.725
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017293
Scope note: The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.
Annotation: a blood protein; an anticoagulant
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Protein S Deficiency
Pharm Action: Anticoagulants
Previous Indexing: Glycoproteins (1980-1992)
Vitamin K (1979-1980)
Public MeSH Note: 93; PROTEIN S, VITAMIN K-DEPENDENT was indexed under GLYCOPROTEINS 1980-92, & VITAMIN K 1979-80
Online Note: use PROTEIN S (NM) to search PROTEIN S, VITAMIN K-DEPENDENT 1980-92
History Note: 93; was PROTEIN S, VITAMIN K-DEPENDENT (NM) 1979-92
DeCS ID: 30593
Unique ID: D017293
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2013/07/09
Protein S - Preferred
Concept UI M0026253
Scope note The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.
Preferred term Protein S
Entry term(s) Cofactor Protein S
Protein S, Cofactor
Protein S, Vitamin K Dependent
Protein S, Vitamin K-Dependent
Vitamin K Dependent Protein S
Vitamin K-Dependent Protein S



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