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Descriptor English: Imipenem
Descriptor Spanish: Imipenem
Descriptor imipenem
Entry term(s) N-formimidoiltienamicina
imipemida
Scope note: Tienamicina semisintética con amplio espectro de actividad antibacteriana frente a bacterias grampositivas y gramnegativas, aerobias y anaerobias, incluyendo cepas multirresistentes. Es estable frente a las betalactamasas. Estudios clínicos han demostrado alta eficacia en el tratamiento de infecciones de diversos sistemas corporales. Su efectividad se incrementa cuando se administra en combinación con CILASTATINA, un inhibidor de la dipeptidasa renal.
Descriptor Portuguese: Imipenem
Descriptor French: Imipénem
Entry term(s): Imipénem anhydre
MK-0787
MK0787
Tree number(s): D02.065.589.099.124.300.500
D03.633.100.300.124.300.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015378
Scope note: Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Registry Number: 71OTZ9ZE0A
CAS Type 1 Name: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))-
DeCS ID: 28157
Unique ID: D015378
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/06/03
Revision Date: 2016/05/31
Imipénem - Preferred
Concept UI M0023689
Preferred term Imipénem
Imipénem anhydre - Narrower
Concept UI M0329530
Preferred term Imipénem anhydre
MK-0787 - Narrower
Concept UI M0351093
Preferred term MK-0787
Entry term(s) MK0787



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