DeCS

Descriptor English:

Imipenem

Descriptor Spanish:

Imipenem

Spanish from Spain

Descriptor	imipenem
Entry term(s)	N-formimidoiltienamicina imipemida
Scope note:	Tienamicina semisintética con amplio espectro de actividad antibacteriana frente a bacterias grampositivas y gramnegativas, aerobias y anaerobias, incluyendo cepas multirresistentes. Es estable frente a las betalactamasas. Estudios clínicos han demostrado alta eficacia en el tratamiento de infecciones de diversos sistemas corporales. Su efectividad se incrementa cuando se administra en combinación con CILASTATINA, un inhibidor de la dipeptidasa renal.

Descriptor Portuguese:

Imipenem

Descriptor French:

Imipénem

Entry term(s):

Imipénem anhydre
MK-0787
MK0787

Tree number(s):

D02.065.589.099.124.300.500
D03.633.100.300.124.300.500

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D015378

Scope note:

Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Anti-Bacterial Agents

Registry Number:

71OTZ9ZE0A

CAS Type 1 Name:

1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))-

DeCS ID:

28157

Unique ID:

D015378

NLM Classification:

QV 350