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Descriptor English: Gonadotropin-Releasing Hormone
Descriptor Spanish: Hormona Liberadora de Gonadotropina
Descriptor hormona liberadora de gonadotropinas
Entry term(s) GnRH
LH-RH
gonadoliberina
hormona liberadora de FSH
hormona liberadora de LH y FSH
hormona liberadora de hormona luteinizante
luliberina
Scope note: Decapéptido que estimula la síntesis y secreción de ambas gonadotropinas hipofisarias, la HORMONA LUTEINIZANTE y la HORMONA FOLICULOESTIMULANTE. La GnRH es producida por neuronas del ÁREA PREÓPTICA del HIPOTÁLAMO, y se libera en la circulación portal hipofisaria, dando lugar a la estimulación de CÉLULAS GONADOTROPAS de la ADENOHIPÓFISIS.
Descriptor Portuguese: Hormônio Liberador de Gonadotropina
Descriptor French: Hormone de libération des gonadotrophines
Entry term(s): Cystorelin
Dirigestran
FSH Releasing Hormone
FSH-Releasing Hormone
Factrel
Gn-RH
GnRH
Gonadoliberin
Gonadorelin
Gonadorelin Acetate
Gonadorelin Hydrochloride
Gonadotropin Releasing Hormone
Kryptocur
LFRH
LH FSH Releasing Hormone
LH Releasing Hormone
LH-FSH Releasing Hormone
LH-RH
LH-Releasing Hormone
LHFSH Releasing Hormone
LHFSHRH
LHRH
Luliberin
Luteinizing Hormone Releasing Hormone
Luteinizing Hormone-Releasing Hormone
Releasing Hormone, LHFSH
Tree number(s): D06.472.699.327.740.320
D12.644.400.400.740.320
D12.644.456.460
D12.644.548.365.740.320
D12.776.631.650.405.740.320
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007987
Scope note: A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 33515-09-2
CAS Type 1 Name: 5-oxoPro-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (human or pig)
Public MeSH Note: 2007; see PITUITARY HORMONE RELEASING HORMONES 1977-1990, see LH-FSH RELEASING HORMONE 1974-1990
History Note: 2007 (1974)
Related: Kallmann Syndrome MeSH
Receptors, LHRH MeSH
DeCS ID: 29311
Unique ID: D007987
NLM Classification: WK 515
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/11/23
Gonadotropin-Releasing Hormone - Preferred
Concept UI M0012446
Scope note A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Preferred term Gonadotropin-Releasing Hormone
Entry term(s) FSH Releasing Hormone
FSH-Releasing Hormone
Gn-RH
GnRH
Gonadoliberin
Gonadorelin
Gonadotropin Releasing Hormone
LFRH
LH FSH Releasing Hormone
LH Releasing Hormone
LH-FSH Releasing Hormone
LH-RH
LH-Releasing Hormone
LHFSH Releasing Hormone
LHFSHRH
LHRH
Luliberin
Luteinizing Hormone Releasing Hormone
Luteinizing Hormone-Releasing Hormone
Releasing Hormone, LHFSH
Factrel - Narrower
Concept UI M0012447
Preferred term Factrel
Cystorelin - Narrower
Concept UI M0012448
Preferred term Cystorelin
Gonadorelin Hydrochloride - Narrower
Concept UI M0331412
Preferred term Gonadorelin Hydrochloride
Kryptocur - Narrower
Concept UI M0012450
Preferred term Kryptocur
Dirigestran - Narrower
Concept UI M0012449
Preferred term Dirigestran
Gonadorelin Acetate - Narrower
Concept UI M0331413
Preferred term Gonadorelin Acetate



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