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Descriptor English: src-Family Kinases
Descriptor Spanish: Familia-src Quinasas
Descriptor cinasas de la familia src
Entry term(s) cinasa Src
cinasa de la familia Src
cinasas src
proteína tirosina cinasas src
proteína tirosina quinasas src
quinasas src
tirosina-cinasa Src
tirosina-cinasa de la familia Src
Scope note: Familia de PROTEINA-TIROSINA QUINASAS originalmente identificada por homología con la PROTEÍNA DEL ONCOGÉN PP60(V-SRC) del virus del sarcoma de Rous. Interactúan con distintos receptores de la superficie celular y participan en vías intracelulares de transducción de señales. Existen formas oncogénicas de quinasas de la familia src, producidas por alteración de la regulación o expresión de la proteína endógena y por genes src (v-src) codificados por virus.
Descriptor Portuguese: Quinases da Família src
Descriptor French: src-Family kinases
Entry term(s): Kinase, src
Kinase, src Tyrosine
Kinase, src-Family
Kinase, src-Family Tyrosine
Kinases, src
Kinases, src Protein-Tyrosine
Kinases, src Tyrosine
Protein-Tyrosine Kinases, src
Src Family Tyrosine Kinase
Tyrosine Kinase, src
Tyrosine Kinase, src-Family
Tyrosine Kinases, src
Tyrosine Kinases, src-Family
src Family Kinase
src Family Kinases
src Family Tyrosine Kinases
src Kinase
src Kinases
src Protein-Tyrosine Kinases
src Tyrosine Kinase
src Tyrosine Kinases
src-Family Kinase
src-Family Tyrosine Kinase
src-Family Tyrosine Kinases
Tree number(s): D08.811.913.696.620.682.725.800
D12.776.476.568.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019061
Scope note: A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.10.2
Previous Indexing: Protein-Tyrosine Kinase (1986-1995)
Public MeSH Note: 96
History Note: 96
Related: src Homology Domains MeSH
DeCS ID: 32603
Unique ID: D019061
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2020/05/27
src-Family Kinases - Preferred
Concept UI M0028454
Scope note A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
Preferred term src-Family Kinases
Entry term(s) Kinase, src
Kinase, src Tyrosine
Kinase, src-Family
Kinase, src-Family Tyrosine
Kinases, src
Kinases, src Protein-Tyrosine
Kinases, src Tyrosine
Protein-Tyrosine Kinases, src
Src Family Tyrosine Kinase
Tyrosine Kinase, src
Tyrosine Kinase, src-Family
Tyrosine Kinases, src
Tyrosine Kinases, src-Family
src Family Kinase
src Family Kinases
src Family Tyrosine Kinases
src Kinase
src Kinases
src Protein-Tyrosine Kinases
src Tyrosine Kinase
src Tyrosine Kinases
src-Family Kinase
src-Family Tyrosine Kinase
src-Family Tyrosine Kinases



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