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Descriptor English: Deoxyribonuclease IV (Phage T4-Induced)
Descriptor Spanish: Desoxirribonucleasa IV (Fago T4-Inducido)
Descriptor desoxirribonucleasa IV (inducida por el fago T4)
Entry term(s) endodesoxirribonucleasa IV (inducida por el fago T4)
endonucleasa IV
Scope note: Enzima que cataliza la escisión endonucleolítica de enlaces fosfodiéster en sitios purínicos o apirimidínicos (sitios AP) para dar lugar a productos finales 5'-fosfooligonucleotídicos. La enzima tiene preferencia por el ADN monocatenario (ssDNA) y anteriormente fue clasificada como EC 3.1.4.30.
Descriptor Portuguese: Desoxirribonuclease IV (Fago T4-Induzido)
Descriptor French: Deoxyribonuclease IV (phage T4-induced)
Entry term(s): Deoxyriboendonuclease IV
Endonuclease IV
Redoxyendonuclease
Tree number(s): D08.811.277.352.335.350.275
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D043223
Scope note: An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.21.2
Previous Indexing: Endodeoxyribonucleases (1987-2003)
Public MeSH Note: 2004; DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED) was indexed under ENDODEOXYRIBONUCLEASES 1987-2003
History Note: 2004; use DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED) (NM) 1987-2002
DeCS ID: 38143
Unique ID: D043223
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2013/07/09
Deoxyribonuclease IV (Phage T4-Induced) - Preferred
Concept UI M0151167
Scope note An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.
Preferred term Deoxyribonuclease IV (Phage T4-Induced)
Entry term(s) Deoxyriboendonuclease IV
Endonuclease IV
Redoxyendonuclease



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