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Descriptor English: Transcription Activator-Like Effector Nucleases
Descriptor Spanish: Nucleasas de los Efectores Tipo Activadores de la Transcripción
Descriptor nucleasas de los efectores tipo activadores de la transcripción
Entry term(s) TALEN
TALENs
nucleasas efectoras tipo activadores de la transcripción
Scope note: Nucleasas artificiales que escinden el ADN a una distancia definida de secuencias específicas de ADN, reconocidas por EFECTORES TIPO ACTIVADORES DE LA TRANSCRIPCIÓN. Están formadas por una endodesoxirribonucleasa unida a dominios de unión al ADN de los efectores tipo activadores de la transcripción.
Descriptor Portuguese: Nucleases dos Efetores Semelhantes a Ativadores de Transcrição
Descriptor French: Nucléases effectrices de type activateur de transcription
Entry term(s): Nucleases, Transcription Activator Like Effector
Nucleases, Transcription Activator-Like Effector
TALEN
TALENs
Transcription Activator Like Effector Nucleases
Tree number(s): D08.811.277.352.335.350.850
D12.776.828.300.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069896
Scope note: Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.-
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56473
Unique ID: D000069896
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27
Transcription Activator-Like Effector Nucleases - Preferred
Concept UI M000608253
Scope note Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors.
Preferred term Transcription Activator-Like Effector Nucleases
Entry term(s) Nucleases, Transcription Activator Like Effector
Nucleases, Transcription Activator-Like Effector
TALEN
TALENs
Transcription Activator Like Effector Nucleases



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