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Descriptor English: Sarcosine Dehydrogenase
Descriptor Spanish: Sarcosina-Deshidrogenasa
Descriptor sarcosina deshidrogenasa
Scope note: Flavoenzima de la matriz mitocondrial del HÍGADO que cataliza la oxidación de la SARCOSINA a GLICINA y FORMALDEHÍDO. La mutación de esta enzima causa sarcosinemia, un defecto metabólico poco frecuente caracterizado por concentraciones elevadas de SARCOSINA en la SANGRE y ORINA.
Descriptor Portuguese: Sarcosina Desidrogenase
Descriptor French: Sarcosine dehydrogenase
Entry term(s): Dehydrogenase, Monomethylglycine
Dehydrogenase, Sarcosine
Monomethylglycine Dehydrogenase
N-Demethylase, Sarcosine
Sarcosine N Demethylase
Sarcosine N-Demethylase
Tree number(s): D08.811.682.662.582.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050892
Scope note: A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.5.8.3
Public MeSH Note: 2006; SARCOSINE DEHYDROGENASE was indexed under OXIDOREDUCTASES, N-DEMETHYLATING 1976-2004, & under SARCOSINE 1976-1982
History Note: 2006(1976); use OXIDOREDUCTASES, N-DEMETHYLATING, & SARCOSINE 1976-1979
DeCS ID: 50631
Unique ID: D050892
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/08
Sarcosine Dehydrogenase - Preferred
Concept UI M0078933
Scope note A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
Preferred term Sarcosine Dehydrogenase
Entry term(s) Dehydrogenase, Monomethylglycine
Dehydrogenase, Sarcosine
Monomethylglycine Dehydrogenase
N-Demethylase, Sarcosine
Sarcosine N Demethylase
Sarcosine N-Demethylase



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