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Descriptor English: RecQ Helicases
Descriptor Spanish: RecQ Helicasas
Descriptor RecQ helicasas
Entry term(s) RecQ helicasa
familia RecQ de ADN-helicasas
helicasa RecQ
Scope note: Familia de ADN helicasas relacionadas estructuralmente que desempeñan un papel esencial en el mantenimiento de la integridad del genoma. Las RecQ helicasas fueron descubiertas originalmente en E. COLI y están muy conservadas en organismos eucariotas y procariotas. Las mutaciones genéticas que producen pérdida de la actividad de la RecQ helicasa dan lugar a trastornos asociados a la predisposición al CÁNCER y al envejecimiento prematuro.
Descriptor Portuguese: RecQ Helicases
Descriptor French: RecQ helicases
Entry term(s): ATP Dependent DNA Helicase Q1
ATP Dependent DNA Helicase Q4
ATP Dependent DNA Helicase Q5
ATP-Dependent DNA Helicase Q1
ATP-Dependent DNA Helicase Q4
ATP-Dependent DNA Helicase Q5
DNA Dependent ATPase Q1
DNA Helicase Q1
DNA Helicase RecQL
DNA Helicase RecQL4
DNA Helicase, RecQ like type 2
DNA Helicase, RecQ-like type 2
DNA-Dependent ATPase Q1
Helicase, RECQL1
Helicase, RTS
Helicase, RecQ
Helicase, RecQ2
Helicase, RecQ3
Helicase, RecQ5
Helicase, RecQ5L
Helicase, RecQL
Helicase, RecQL2
Helicase, RecQL3
Helicase, RecQL4
Helicases, RecQ
RECQL1 Helicase
RTS Helicase
RecQ Family of DNA Helicase
RecQ Family of DNA Helicases
RecQ Helicase
RecQ Protein
RecQ2 Helicase
RecQ3 Helicase
RecQ4 Helicase
RecQ5 Helicase
RecQ5L Helicase
RecQL Helicase
RecQL2 Helicase
RecQL3 Helicase
RecQL4 Helicase
Tree number(s): D08.811.277.040.025.159.249
D08.811.399.340.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053484
Scope note: A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.12
Public MeSH Note: 2007: RECQ HELICASES was indexed under ADENOSINE TRIPHOSPHATASES & DNA HELICASES 1990-2006; RECQ4 HELICASE was indexed under DNA HELICASES 2002-2006; DNA HELICASE RECQL was indexed under DNA HELICASES & ADENOSINE TRIPHOSPHATASES 1994-2006; RECQ5 HELICASE was indexed under DNA HELICASES 1999-2006
History Note: 2007(1990)
Related: Bloom Syndrome MeSH
Rothmund-Thomson Syndrome MeSH
Werner Syndrome MeSH
DeCS ID: 52217
Unique ID: D053484
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2020/05/27
RecQ Helicases - Preferred
Concept UI M0178844
Scope note A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.
Preferred term RecQ Helicases
Entry term(s) Helicase, RecQ
Helicases, RecQ
RecQ Family of DNA Helicase
RecQ Family of DNA Helicases
RecQ Helicase
RecQ Protein
RecQL Helicase - Narrower
Concept UI M0239601
Preferred term RecQL Helicase
Entry term(s) ATP Dependent DNA Helicase Q1
ATP-Dependent DNA Helicase Q1
DNA Dependent ATPase Q1
DNA Helicase Q1
DNA Helicase RecQL
DNA-Dependent ATPase Q1
Helicase, RECQL1
Helicase, RecQL
RECQL1 Helicase
RecQ4 Helicase - Narrower
Concept UI M0414891
Preferred term RecQ4 Helicase
Entry term(s) ATP Dependent DNA Helicase Q4
ATP-Dependent DNA Helicase Q4
DNA Helicase RecQL4
Helicase, RTS
Helicase, RecQL4
RTS Helicase
RecQL4 Helicase
RecQ5 Helicase - Narrower
Concept UI M0336412
Preferred term RecQ5 Helicase
Entry term(s) ATP Dependent DNA Helicase Q5
ATP-Dependent DNA Helicase Q5
Helicase, RecQ5
Helicase, RecQ5L
RecQ5L Helicase
RecQ2 Helicase - Narrower
Concept UI M0493665
Preferred term RecQ2 Helicase
Entry term(s) DNA Helicase, RecQ like type 2
DNA Helicase, RecQ-like type 2
Helicase, RecQ2
Helicase, RecQL3
RecQL3 Helicase
RecQ3 Helicase - Narrower
Concept UI M0493666
Preferred term RecQ3 Helicase
Entry term(s) Helicase, RecQ3
Helicase, RecQL2
RecQL2 Helicase



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