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Descriptor English: Xeroderma Pigmentosum Group D Protein
Descriptor Spanish: Proteína de la Xerodermia Pigmentosa del Grupo D
Descriptor proteína de la xerodermia pigmentosa del grupo D
Entry term(s) proteína ERCC2
proteína del xeroderma pigmentoso del grupo D
Scope note: ADN helicasa que es un componente del FACTOR DE TRANSCRIPCIÓN TFIIH. Tiene un papel esencial en la REPARACIÓN DEL ADN y las mutaciones de esta proteína se asocian a la XERODERMIA PIGMENTOSA.
Descriptor Portuguese: Proteína Grupo D do Xeroderma Pigmentoso
Descriptor French: Protéine du groupe de complémentation D de Xeroderma pigmentosum
Entry term(s): ERCC2 Protein
Excision Repair Cross Complementing Rodent Repair Deficiency, Group 2 Protein
Excision Repair Cross-Complementing Rodent Repair Deficiency, Group 2 Protein
Xeroderma Pigmentosum Complementation Group D Protein
Tree number(s): D08.811.277.040.025.159.500
D08.811.399.340.500
D12.776.260.775.875.875.500
D12.776.930.930.875.875.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051759
Scope note: A DNA helicase that is a component of TRANSCRIPTION FACTOR TFIIH. It plays an essential role in NUCLEOTIDE EXCISION REPAIR, and mutations in this protein are associated with XERODERMA PIGMENTOSUM.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.4.12
Public MeSH Note: 2006; XERODERMA PIGMENTOSUM GROUP D PROTEIN was indexed under DNA HELICASES & DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1993-2005, & under PROTEINS 1992
History Note: 2006(1992)
Related: Xeroderma Pigmentosum MeSH
DeCS ID: 50584
Unique ID: D051759
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/08
Xeroderma Pigmentosum Group D Protein - Preferred
Concept UI M0201753
Scope note A DNA helicase that is a component of TRANSCRIPTION FACTOR TFIIH. It plays an essential role in NUCLEOTIDE EXCISION REPAIR, and mutations in this protein are associated with XERODERMA PIGMENTOSUM.
Preferred term Xeroderma Pigmentosum Group D Protein
Entry term(s) ERCC2 Protein
Excision Repair Cross Complementing Rodent Repair Deficiency, Group 2 Protein
Excision Repair Cross-Complementing Rodent Repair Deficiency, Group 2 Protein
Xeroderma Pigmentosum Complementation Group D Protein



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