| Descriptor English: | Ku Autoantigen | ||||||
| Descriptor Spanish: |
Autoantígeno Ku
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| Descriptor Portuguese: | Autoantígeno Ku | ||||||
| Descriptor French: | Autoantigène Ku | ||||||
| Entry term(s): |
Antigen, G22P1 Antigen, Ku Antigen, Ku70 Antigen, Ku80 Autoantigen, Ku G22P1 Antigen Heterodimer, Ku Ku Antigen Ku Autoantigen, 70 kDa Ku Autoantigen, 80 kDa Ku Heterodimer Ku Protein Ku70 Antigen Ku80 Antigen X ray Repair Cross Complementing Protein 5 X ray Repair Cross Complementing Protein 6 X-ray Repair Cross-Complementing Protein 5 X-ray Repair Cross-Complementing Protein 6 XRCC5 Protein XRCC6 Protein |
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| Tree number(s): |
D08.811.277.040.025.159.155 D08.811.399.340.155 D12.776.157.687.493 D12.776.260.525 D12.776.660.625.625 D12.776.660.720.493 D23.050.290.625 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000072200 | ||||||
| Scope note: | An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 4.2.99.- | ||||||
| Public MeSH Note: | 2017; KU AUTOANTIGEN was indexed under DNA-BINDING PROTEINS and ANTIGENS, NUCLEAR 2003-2016; and under ANTIGENS, SURFACE 1986-1991 and NUCLEAR PROTEINS 1985-2003 |
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| History Note: | 2017 (1986) |
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| DeCS ID: | 56468 | ||||||
| Unique ID: | D000072200 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Ku Autoantigen
- Preferred
Ku80 Antigen
- Narrower
Ku70 Antigen
- Narrower
| Concept UI |
M0138075 |
| Scope note | An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION. |
| Preferred term | Ku Autoantigen |
| Entry term(s) |
Antigen, G22P1 Antigen, Ku Autoantigen, Ku G22P1 Antigen Heterodimer, Ku Ku Antigen Ku Heterodimer Ku Protein |
| Concept UI |
M0466161 |
| Preferred term | Ku80 Antigen |
| Entry term(s) |
Antigen, Ku80 Ku Autoantigen, 80 kDa X ray Repair Cross Complementing Protein 5 X-ray Repair Cross-Complementing Protein 5 XRCC5 Protein |
| Concept UI |
M0453319 |
| Preferred term | Ku70 Antigen |
| Entry term(s) |
Antigen, Ku70 Ku Autoantigen, 70 kDa X ray Repair Cross Complementing Protein 6 X-ray Repair Cross-Complementing Protein 6 XRCC6 Protein |
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