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Descriptor English: Protein Tyrosine Phosphatase, Non-Receptor Type 2
Descriptor Spanish: Proteína Tirosina Fosfatasa no Receptora Tipo 2
Descriptor proteína tirosina fosfatasa no receptora de tipo 2
Scope note: Subtipo de proteína tirosina fosfatasa no receptora estrechamente relacionada con la PROTEÍNA TIROSINA FOSFATASA NO RECEPTORA DE TIPO 1. Un empalme alternativo del ARNm de esta fosfatasa da lugar a dos productos génicos, uno de los cuales incluye un dominio de localización nuclear C-terminal que puede estar implicado en el transporte de la proteína al NÚCLEO CELULAR. Aunque inicialmente se lo denominó "proteína tirosina fosfatasa de los linfocitos T", este subtipo se expresa ampliamente.
Descriptor Portuguese: Proteína Tirosina Fosfatase não Receptora Tipo 2
Descriptor French: Protein Tyrosine Phosphatase, Non-Receptor Type 2
Entry term(s): Protein Tyrosine Phosphatase, Non Receptor Type 2
Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform
Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform
T Cell Protein Tyrosine Phosphatase
T-Cell Protein Tyrosine Phosphatase
TC-PTP
TC45 Enzyme
TC45 Protein Tyrosine Phosphatase
TC48 Enzyme
TC48 Protein Tyrosine Phosphatase
TCPTP Enzyme
Tree number(s): D08.811.277.352.650.775.300.200
D12.776.476.564.300.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054578
Scope note: A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.3.48
Public MeSH Note: 2008; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2 was indexed under PROTEIN TYROSINE PHOSPHATASE 1994-2007
History Note: 2008(1994)
DeCS ID: 52697
Unique ID: D054578
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2015/11/24
Protein Tyrosine Phosphatase, Non-Receptor Type 2 - Preferred
Concept UI M0228158
Scope note A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.
Preferred term Protein Tyrosine Phosphatase, Non-Receptor Type 2
Entry term(s) Protein Tyrosine Phosphatase, Non Receptor Type 2
T Cell Protein Tyrosine Phosphatase
T-Cell Protein Tyrosine Phosphatase
TC-PTP
TCPTP Enzyme
Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform - Narrower
Concept UI M0448143
Preferred term Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform
Entry term(s) TC48 Enzyme
TC48 Protein Tyrosine Phosphatase
Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform - Narrower
Concept UI M0404080
Preferred term Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform
Entry term(s) TC45 Enzyme
TC45 Protein Tyrosine Phosphatase



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