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Descriptor English: Protein Tyrosine Phosphatase, Non-Receptor Type 13
Descriptor Spanish: Proteína Tirosina Fosfatasa no Receptora Tipo 13
Descriptor proteína tirosina fosfatasa no receptora de tipo 13
Scope note: Un subtipo de proteínas tirosina fosfatasas no receptoras que se caracteriza por la presencia de un dominio FERM amino-terminal, una región interpuesta que contiene cinco diferentes dominios PDZ y un dominio fosfatasa carboxi-terminal. Además de intervenir como regulador de la actividad del RECEPTOR FAS, este subtipo interactúa a través de sus dominios PDZ y FERM con varias PROTEÍNAS DE SEÑALIZACIÓN INTRACELULAR y PROTEÍNAS CITOESQUELÉTICAS.
Descriptor Portuguese: Proteína Tirosina Fosfatase não Receptora Tipo 13
Descriptor French: Protein Tyrosine Phosphatase, Non-Receptor Type 13
Entry term(s): Phosphatase BAS, Protein-Tyrosine
Protein Tyrosine Phosphatase 1E
Protein Tyrosine Phosphatase BAS
Protein Tyrosine Phosphatase BL
Protein Tyrosine Phosphatase, Basophil Like
Protein Tyrosine Phosphatase, Non Receptor Type 13
Protein-Tyrosine Phosphatase 1E
Protein-Tyrosine Phosphatase BAS
Tree number(s): D08.811.277.352.650.775.300.860
D12.776.476.564.300.860
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054595
Scope note: A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an amino-terminal FERM domain, an intervening region containing five different PDZ domains, and a carboxyl-terminal phosphatase domain. In addition to playing a role as a regulator of the FAS RECEPTOR activity this subtype interacts via its PDZ and FERM domains with a variety of INTRACELLULAR SIGNALING PROTEINS and CYTOSKELETAL PROTEINS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.3.48
Public MeSH Note: 2008; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 13 was indexed under PROTEIN TYROSINE PHOSPHATASES 2001-2007
History Note: 2008(2001)
DeCS ID: 52702
Unique ID: D054595
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2015/11/24
Protein Tyrosine Phosphatase, Non-Receptor Type 13 - Preferred
Concept UI M0391502
Scope note A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an amino-terminal FERM domain, an intervening region containing five different PDZ domains, and a carboxyl-terminal phosphatase domain. In addition to playing a role as a regulator of the FAS RECEPTOR activity this subtype interacts via its PDZ and FERM domains with a variety of INTRACELLULAR SIGNALING PROTEINS and CYTOSKELETAL PROTEINS.
Preferred term Protein Tyrosine Phosphatase, Non-Receptor Type 13
Entry term(s) Phosphatase BAS, Protein-Tyrosine
Protein Tyrosine Phosphatase 1E
Protein Tyrosine Phosphatase BAS
Protein Tyrosine Phosphatase BL
Protein Tyrosine Phosphatase, Basophil Like
Protein Tyrosine Phosphatase, Non Receptor Type 13
Protein-Tyrosine Phosphatase 1E
Protein-Tyrosine Phosphatase BAS



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