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Descriptor English: Mediator Complex Subunit 1
Descriptor Spanish: Subunidad 1 del Complejo Mediador
Descriptor subunidad 1 del complejo mediador
Scope note: Subunidad del complejo mediador que se cree que desempeña un papel clave en la coactivación de la transcripción activada por receptores nucleares. Interactúa con diversos receptores nucleares, incluidos RECEPTORES DE ÁCIDO RETINOICO, RECEPTORES DE HORMONA TIROIDEA, RECEPTORES DE VITAMINA D, RECEPTORES ACTIVADOS POR PROLIFERADORES DE PEROXISOMAS, RECEPTORES ESTROGÉNICOS y RECEPTORES DE GLUCOCORTICOIDES. 
Descriptor Portuguese: Subunidade 1 do Complexo Mediador
Descriptor French: Sous-unité-1 du complexe médiateur
Entry term(s): DRIP205
Mediator of RNA Polymerase II Transcription Subunit 1
PPAR Binding Protein
PPAR-Binding Protein
Peroxisome Proliferator Activated Receptor Binding Protein
Peroxisome Proliferator-Activated Receptor Binding Protein
RB18A
TR Associated Protein P220
TR-Associated Protein P220
TRAP220
TRIP2 (Thyroid Receptor Interacting Protein 2)
Thyroid Hormone Receptor Associated Protein 220
Thyroid Receptor Interacting Protein 2
Vitamin D Receptor Interacting Protein Complex Component DRIP205
Vitamin D Receptor-Interacting Protein Complex Component DRIP205
p53 Regulatory Protein RB18A
Tree number(s): D05.500.374.750
D12.644.360.024.309.750
D12.644.360.024.314.049
D12.776.157.057.072.750
D12.776.157.057.080.049
D12.776.476.024.388.750
D12.776.476.024.394.049
D12.776.660.551.750
D12.776.660.675.049
D12.776.930.617.049
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056913
Scope note: A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTIION SUBUNIT 1 (now MEDIATOR COMPLEX SUBUNIT 1) was indexed under TRANSCRIPTION FACTORS 1998-2009
History Note: 2010(1998)
DeCS ID: 53576
Unique ID: D056913
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2016/03/30
Mediator Complex Subunit 1 - Preferred
Concept UI M0533369
Scope note A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.
Preferred term Mediator Complex Subunit 1
Entry term(s) DRIP205
Mediator of RNA Polymerase II Transcription Subunit 1
PPAR Binding Protein
PPAR-Binding Protein
Peroxisome Proliferator Activated Receptor Binding Protein
Peroxisome Proliferator-Activated Receptor Binding Protein
RB18A
TR Associated Protein P220
TR-Associated Protein P220
TRAP220
TRIP2 (Thyroid Receptor Interacting Protein 2)
Thyroid Hormone Receptor Associated Protein 220
Thyroid Receptor Interacting Protein 2
Vitamin D Receptor Interacting Protein Complex Component DRIP205
Vitamin D Receptor-Interacting Protein Complex Component DRIP205
p53 Regulatory Protein RB18A



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