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Descriptor English: Nuclear Receptor Coactivator 1
Descriptor Spanish: Coactivador 1 de Receptor Nuclear
Descriptor coactivador 1 de receptores nucleares
Scope note: Un coactivador del receptor nuclear con especificidad para RECEPTORES DE ESTRÓGENO, RECEPTORES DE PROGESTERONA y RECEPTORES DE HORMONAS TIROIDEAS. Tiene una actividad HISTONA ACETILTRANSFERASA que puede desempeñar un papel en la activación transcripcional de regiones de la CROMATINA.
Descriptor Portuguese: Coativador 1 de Receptor Nuclear
Descriptor French: Coactivateur-1 de récepteur nucléaire
Entry term(s): NCoA 1 Protein
NCoA-1 Protein
Nuclear Receptor Coactivator-1
Steroid Receptor Coactivator 1
Tree number(s): D08.811.913.050.134.415.500.100
D12.644.360.024.314.100
D12.776.157.057.080.100
D12.776.260.103.782
D12.776.476.024.394.100
D12.776.660.675.100
D12.776.930.125.500.625
D12.776.930.617.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056920
Scope note: A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and THYROID HORMONE RECEPTORS. It contains a HISTONE ACETYLTRANSFRASE activity that may play a role in the transcriptional activation of CHROMATIN regions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.1.48
Public MeSH Note: 2010; NUCLEAR RECEPTOR COACTIVATOR 1 was indexed under TRANSCRIPTION FACTORS and HISTONE ACETYLTRANSFERASES 1995-2009
History Note: 2010(1995)
DeCS ID: 53610
Unique ID: D056920
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2016/04/15
Nuclear Receptor Coactivator 1 - Preferred
Concept UI M0533381
Scope note A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and THYROID HORMONE RECEPTORS. It contains a HISTONE ACETYLTRANSFRASE activity that may play a role in the transcriptional activation of CHROMATIN regions.
Preferred term Nuclear Receptor Coactivator 1
Entry term(s) NCoA 1 Protein
NCoA-1 Protein
Nuclear Receptor Coactivator-1
Steroid Receptor Coactivator 1



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