Descriptor English: | Fibrillins | ||||||
Descriptor Spanish: |
Fibrilinas
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Descriptor Portuguese: | Fibrilinas | ||||||
Descriptor French: | Fibrillines | ||||||
Entry term(s): |
Fibrillin |
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Tree number(s): |
D09.400.430.800 D12.776.395.341 D12.776.860.300.400 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071837 | ||||||
Scope note: | A family of extracellular matrix glycoproteins that is structurally similar to LATENT TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting of growth factors to the extracellular matrix. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Public MeSH Note: | 2017; see FIBRILLIN 1985-2016 |
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History Note: | 2017; use FIBRILLIN 1985-2016 |
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DeCS ID: | 56519 | ||||||
Unique ID: | D000071837 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2017/01/01 | ||||||
Date of Entry: | 2016/07/08 | ||||||
Revision Date: | 2016/04/15 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Fibrillins
- Preferred
Concept UI |
M000615581 |
Scope note | A family of extracellular matrix glycoproteins that is structurally similar to LATENT TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting of growth factors to the extracellular matrix. |
Preferred term | Fibrillins |
Entry term(s) |
Fibrillin |
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