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Descriptor English: Laminin
Descriptor Spanish: Laminina
Descriptor laminina
Entry term(s) merosina
Scope note: Gran glicoproteína no colágeno con propiedades antigénicas. Se localiza en la membrana basal de la lámina lúcida y funciona uniendo las células epiteliales a las membranas basales. Las evidencias sugieren que esta proteína interviene en la invasión tumoral.
Descriptor Portuguese: Laminina
Descriptor French: Laminine
Entry term(s): Chain, Laminin M
Glycoprotein GP 2
Glycoprotein GP-2
Laminin M
Laminin M Chain
M Chain, Laminin
Merosin
Tree number(s): D09.400.430.890.530
D12.776.395.550.530
D12.776.543.550.500
D12.776.860.300.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007797
Scope note: Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.
Annotation: an extracellular matrix protein; /biosyn /physiol permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Glycoproteins (1966-1983)
Membrane Proteins (1977-1983)
Neoplasm Proteins (1966-1983)
Public MeSH Note: 84
History Note: 84
Related: Receptors, Laminin MeSH
DeCS ID: 29462
Unique ID: D007797
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1983/05/31
Revision Date: 1996/06/10
Laminin - Preferred
Concept UI M0012194
Scope note Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.
Preferred term Laminin
Entry term(s) Glycoprotein GP 2
Glycoprotein GP-2
Merosin - Narrower
Concept UI M0012197
Preferred term Merosin
Laminin M - Narrower
Concept UI M0012195
Preferred term Laminin M
Laminin M Chain - Narrower
Concept UI M0012196
Preferred term Laminin M Chain
Entry term(s) Chain, Laminin M
M Chain, Laminin



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