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Descriptor English: Panitumumab
Descriptor Spanish: Panitumumab
Descriptor panitumumab
Entry term(s) ABX-EGF MAb
anticuerpo humano panitumumab
anticuerpo monoclonal ABX EGF
anticuerpo monoclonal ABX-EGF
vectibix
Scope note: Anticuerpo monoclonal humano recombinante que se une al RECEPTOR DEL FACTOR DE CRECIMIENTO EPIDÉRMICO e inhibe su función. Se usa en el tratamiento del cáncer colorrectal metastásico con expresión del EGFR que expresa el gen ras natural (ver GENES RAS).
Descriptor Portuguese: Panitumumabe
Descriptor French: Panitumumab
Entry term(s): ABX EGF Monoclonal Antibody
ABX-EGF MAb
ABX-EGF Monoclonal Antibody
Human Panitumumab Antibody
Monoclonal Antibody, ABX-EGF
Panitumumab Antibody, Human
Vectibix
Tree number(s): D12.776.124.486.485.114.224.060.864
D12.776.124.790.651.114.224.060.864
D12.776.377.715.548.114.224.200.864
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077544
Scope note: Recombinant human monoclonal antibody that binds to and inhibits the function of the EPIDERMAL GROWTH FACTOR RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene (see GENES, RAS).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Antineoplastic Agents, Immunological
Registry Number: 6A901E312A
CAS Type 1 Name: Immunoglobulin, anti-(human epidermal growth factor receptor) (human monoclonal ABX-EGF heavy chain), disulfide with human monoclonal ABX-EGF light chain, dimer
Public MeSH Note: 2019; PANITUMUMAB was indexed under ANTIBODIES, MONOCLONAL 2005-2018
History Note: 2019 (2005)
DeCS ID: 57669
Unique ID: D000077544
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Panitumumab - Preferred
Concept UI M0484911
Scope note Recombinant human monoclonal antibody that binds to and inhibits the function of the EPIDERMAL GROWTH FACTOR RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene (see GENES, RAS).
Preferred term Panitumumab
Entry term(s) ABX EGF Monoclonal Antibody
ABX-EGF MAb
ABX-EGF Monoclonal Antibody
Human Panitumumab Antibody
Monoclonal Antibody, ABX-EGF
Panitumumab Antibody, Human
Vectibix - Narrower
Concept UI M0502224
Preferred term Vectibix



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