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Descriptor English: Basiliximab
Descriptor Spanish: Basiliximab
Descriptor basiliximab
Entry term(s) CHI 621
SDZ CHI 621
Simulect
Scope note: Anticuerpo monoclonal quimérico murino-humano que actúa como antagonista de los RECEPTORES DE INTERLEUCINA-2 al unirse a la cadena alfa (ANTÍGENO CD25) del receptor de la interleucina-2 en la superficie de los LINFOCITOS T activados. Se usa en la prevención de los episodios de rechazo agudo de injertos en pacientes que se someten a un trasplante renal.
Descriptor Portuguese: Basiliximab
Descriptor French: Basiliximab
Entry term(s): CHI 621
SDZ CHI 621
Simulect
Tree number(s): D12.776.124.486.485.114.224.060.344
D12.776.124.790.651.114.224.060.407
D12.776.377.715.548.114.224.200.407
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077552
Scope note: A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of the interleukin-2 receptor on the surface of activated T-LYMPHOCYTES. It is used in the prevention of acute graft rejection episodes in patients undergoing renal transplantation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunosuppressive Agents
Registry Number: 9927MT646M
Public MeSH Note: 2019; BASILIXIMAB was indexed under ANTIBODIES, MONOCLONAL and RECOMBINANT FUSION PROTEINS 1998-2018
History Note: 2019 (1998)
DeCS ID: 57677
Unique ID: D000077552
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Basiliximab - Preferred
Concept UI M0292349
Scope note A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of the interleukin-2 receptor on the surface of activated T-LYMPHOCYTES. It is used in the prevention of acute graft rejection episodes in patients undergoing renal transplantation.
Preferred term Basiliximab
Simulect - Narrower
Concept UI M0294876
Preferred term Simulect
CHI 621 - Narrower
Concept UI M0294877
Preferred term CHI 621
Entry term(s) SDZ CHI 621



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