| Descriptor English: | Antibodies, Monoclonal, Humanized | ||||||
| Descriptor Spanish: |
Anticuerpos Monoclonales Humanizados
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| Descriptor Portuguese: | Anticorpos Monoclonais Humanizados | ||||||
| Descriptor French: | Anticorps monoclonaux humanisés | ||||||
| Entry term(s): |
Antibodies, Humanized Humanized Antibodies |
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| Tree number(s): |
D12.776.124.486.485.114.224.060 D12.776.124.790.651.114.224.060 D12.776.377.715.548.114.224.200 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D061067 | ||||||
| Scope note: | Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Antibodies, Monoclonal (1991-2011) |
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| Public MeSH Note: | 2012 |
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| History Note: | 2012 |
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| DeCS ID: | 54578 | ||||||
| Unique ID: | D061067 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2012/01/01 | ||||||
| Date of Entry: | 2011/06/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Antibodies, Monoclonal, Humanized
- Preferred
| Concept UI |
M0556300 |
| Scope note | Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab. |
| Preferred term | Antibodies, Monoclonal, Humanized |
| Entry term(s) |
Antibodies, Humanized Humanized Antibodies |
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