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Descriptor in English: Guanethidine
Descriptor in Spanish: Guanetidina
Descriptor in Portuguese: Guanetidina
Descriptor in French: Guanéthidine
Entry term(s): ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
Guanethidine Monosulfate
Guanethidine Sulfate
Guanethidine Sulfate (1:1)
Guanethidine Sulfate (1:2)
Guanethidine Sulfate (2:1)
Guanethidine Sulfate (2:1), 14C-Labeled
Ismelin
Isobarin
Monosulfate, Guanethidine
Octadine
Oktadin
Sulfate, Guanethidine
Tree number(s): D02.078.370.460
Scope note: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
DeCS UI: 6295
Descriptor UI: D006145
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Guanethidine - Preferred
Concept UI M0009675
Scope note An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Preferred term Guanethidine
Entry term(s) ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
Octadine
Oktadin
Guanethidine Sulfate - Narrower
Concept UI M0350959
Preferred term Guanethidine Sulfate
Entry term(s) Guanethidine Sulfate (2:1)
Sulfate, Guanethidine
Guanethidine Sulfate (1:2) - Narrower
Concept UI M0330234
Preferred term Guanethidine Sulfate (1:2)
Ismelin - Narrower
Concept UI M0350958
Preferred term Ismelin
Isobarin - Narrower
Concept UI M0009676
Preferred term Isobarin
Guanethidine Monosulfate - Narrower
Concept UI M0330236
Preferred term Guanethidine Monosulfate
Entry term(s) Guanethidine Sulfate (1:1)
Monosulfate, Guanethidine
Guanethidine Sulfate (2:1), 14C-Labeled - Narrower
Concept UI M0330237
Preferred term Guanethidine Sulfate (2:1), 14C-Labeled



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