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Descriptor English: Pyrimethamine
Descriptor Spanish: Pirimetamina
Descriptor pirimetamina
Scope note: Antagonista de ácido fólico que se emplea como fármaco antipalúdico o, asociado a sulfonamida, para el tratamiento de la toxoplasmosis.
Descriptor Portuguese: Pirimetamina
Descriptor French: Pyriméthamine
Entry term(s): Chloridin
Daraprim
Malocide
Tindurine
Tree number(s): D03.383.742.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011739
Scope note: One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimalarials
Antiprotozoal Agents
Folic Acid Antagonists
Registry Number: Z3614QOX8W
CAS Type 1 Name: 2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-
DeCS ID: 12176
Unique ID: D011739
NLM Classification: QV 256
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Pyrimethamine - Preferred
Concept UI M0018253
Scope note One of the FOLIC ACID ANTAGONISTS that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Preferred term Pyrimethamine
Malocide - Narrower
Concept UI M0476076
Preferred term Malocide
Tindurine - Narrower
Concept UI M0373205
Preferred term Tindurine
Chloridin - Narrower
Concept UI M0373206
Preferred term Chloridin
Daraprim - Narrower
Concept UI M0018254
Preferred term Daraprim



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