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Descriptor English: Pyrithiamine
Descriptor Spanish: Piritiamina
Descriptor Portuguese: Piritiamina
Descriptor French: Pyrithiamine
Entry term(s): 1, Heterovitamin B
B 1, Heterovitamin
Heterovitamin B 1
Neopyrithiamine
Tree number(s): D03.383.725.762.760
D03.383.742.715
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011745
Scope note: A thiamine antagonist due to its inhibition of thiamine pyrophosphorylation. It is used to produce thiamine deficiency.
Annotation: a thiamine antag
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Registry Number: 5JB3029BJ7
CAS Type 1 Name: Pyridinium, 1-((4-amino-2-methyl-5-pyrimidinyl)methyl)-3-(2-hydroxyethyl)-2-methyl-, bromide, monohydrobromide
Previous Indexing: Pyridinium Compounds (1974-1976)
Pyrimidines (1974-1976)
Public MeSH Note: 91; was see under PYRIDINIUM COMPOUNDS 1977-90
History Note: 91(77); was see under PYRIDINIUM COMPOUNDS 1977-90
DeCS ID: 12182
Unique ID: D011745
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/13
Revision Date: 2016/05/31
Pyrithiamine - Preferred
Concept UI M0018263
Scope note A thiamine antagonist due to its inhibition of thiamine pyrophosphorylation. It is used to produce thiamine deficiency.
Preferred term Pyrithiamine
Entry term(s) 1, Heterovitamin B
B 1, Heterovitamin
Heterovitamin B 1
Neopyrithiamine



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