Descriptor English: | Pyrithiamine | ||||||
Descriptor Spanish: |
Piritiamina
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Descriptor Portuguese: | Piritiamina | ||||||
Descriptor French: | Pyrithiamine | ||||||
Entry term(s): |
1, Heterovitamin B B 1, Heterovitamin Heterovitamin B 1 Neopyrithiamine |
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Tree number(s): |
D03.383.725.762.760 D03.383.742.715 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011745 | ||||||
Scope note: | A thiamine antagonist due to its inhibition of thiamine pyrophosphorylation. It is used to produce thiamine deficiency. |
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Annotation: | a thiamine antag |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Antimetabolites |
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Registry Number: | 5JB3029BJ7 | ||||||
CAS Type 1 Name: | Pyridinium, 1-((4-amino-2-methyl-5-pyrimidinyl)methyl)-3-(2-hydroxyethyl)-2-methyl-, bromide, monohydrobromide | ||||||
Previous Indexing: |
Pyridinium Compounds (1974-1976) Pyrimidines (1974-1976) |
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Public MeSH Note: | 91; was see under PYRIDINIUM COMPOUNDS 1977-90 |
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History Note: | 91(77); was see under PYRIDINIUM COMPOUNDS 1977-90 |
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DeCS ID: | 12182 | ||||||
Unique ID: | D011745 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1991/01/01 | ||||||
Date of Entry: | 1976/04/13 | ||||||
Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Pyrithiamine
- Preferred
Concept UI |
M0018263 |
Scope note | A thiamine antagonist due to its inhibition of thiamine pyrophosphorylation. It is used to produce thiamine deficiency. |
Preferred term | Pyrithiamine |
Entry term(s) |
1, Heterovitamin B B 1, Heterovitamin Heterovitamin B 1 Neopyrithiamine |
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