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Descriptor English: Rilpivirine
Descriptor Spanish: Rilpivirina
Descriptor Portuguese: Rilpivirina
Descriptor French: Rilpivirine
Entry term(s): 278, TMC
HCl, Rilpivirine
Hydrochloride, Rilpivirine
R278474
Rilpivirine HCl
Rilpivirine Hydrochloride
TMC 278
TMC-278
TMC278
Tree number(s): D02.626.809
D03.383.742.755
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068696
Scope note: A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Reverse Transcriptase Inhibitors
Anti-HIV Agents
Registry Number: FI96A8X663
Public MeSH Note: 2016; RILPIVIRINE was indexed under NITRILES 2005-2015, and under PYRIMIDINES 2005-2015
History Note: 2016 (2005)
DeCS ID: 55897
Unique ID: D000068696
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/31
Rilpivirine - Preferred
Concept UI M0482137
Scope note A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone.
Preferred term Rilpivirine
Rilpivirine Hydrochloride - Narrower
Concept UI M000603537
Preferred term Rilpivirine Hydrochloride
Entry term(s) HCl, Rilpivirine
Hydrochloride, Rilpivirine
Rilpivirine HCl
R278474 - Narrower
Concept UI M0482138
Preferred term R278474
TMC 278 - Narrower
Concept UI M0493524
Preferred term TMC 278
Entry term(s) 278, TMC
TMC-278
TMC278



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