| Descriptor English: | Rilpivirine | ||||
| Descriptor Spanish: |
Rilpivirina
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| Descriptor Portuguese: | Rilpivirina | ||||
| Descriptor French: | Rilpivirine | ||||
| Entry term(s): |
278, TMC HCl, Rilpivirine Hydrochloride, Rilpivirine R278474 Rilpivirine HCl Rilpivirine Hydrochloride TMC 278 TMC-278 TMC278 |
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| Tree number(s): |
D02.626.809 D03.383.742.755 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000068696 | ||||
| Scope note: | A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Reverse Transcriptase Inhibitors Anti-HIV Agents |
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| Registry Number: | FI96A8X663 | ||||
| Public MeSH Note: | 2016; RILPIVIRINE was indexed under NITRILES 2005-2015, and under PYRIMIDINES 2005-2015 |
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| History Note: | 2016 (2005) |
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| DeCS ID: | 55897 | ||||
| Unique ID: | D000068696 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2016/01/01 | ||||
| Date of Entry: | 2015/07/01 | ||||
| Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Rilpivirine
- Preferred
Rilpivirine Hydrochloride
- Narrower
R278474
- Narrower
TMC 278
- Narrower
| Concept UI |
M0482137 |
| Scope note | A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone. |
| Preferred term | Rilpivirine |
| Concept UI |
M000603537 |
| Preferred term | Rilpivirine Hydrochloride |
| Entry term(s) |
HCl, Rilpivirine Hydrochloride, Rilpivirine Rilpivirine HCl |
| Concept UI |
M0482138 |
| Preferred term | R278474 |
| Concept UI |
M0493524 |
| Preferred term | TMC 278 |
| Entry term(s) |
278, TMC TMC-278 TMC278 |
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