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Descriptor English: Complement C6
Descriptor Spanish: Complemento C6
Descriptor complemento C6
Scope note: Glicoproteína sérica de 105 kDa con homología significativa con otros componentes tardíos del complemento, C7-C9. Es una cadena polipeptídica entrecruzada por 32 puentes disulfuro. C6 es el siguiente componente del complemento que se une al COMPLEMENTO C5B unido a la membrana en el ensamblaje del COMPLEJO DE ATAQUE A LA MEMBRANA. Está codificada por el gen C6.
Descriptor Portuguese: Complemento C6
Descriptor French: Complément C6
Entry term(s): C6 Complement
C6, Complement
Complement 6
Complement Component 6
Complement, C6
Component 6, Complement
Tree number(s): D12.776.124.486.274.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003183
Scope note: A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Previous Indexing: Complement (1968-1974)
Public MeSH Note: 2006; see COMPLEMENT 6 1978-2005, see COMPLEMENT 1975-1977
History Note: 2006 (1975)
DeCS ID: 22138
Unique ID: D003183
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2005/06/30
Complement C6 - Preferred
Concept UI M0004938
Scope note A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
Preferred term Complement C6
Entry term(s) C6 Complement
C6, Complement
Complement 6
Complement Component 6
Complement, C6
Component 6, Complement



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