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Descriptor English: Immunoglobulin Variable Region
Descriptor Spanish: Región Variable de Inmunoglobulina
Descriptor región variable de las inmunoglobulinas
Entry term(s) región variable de Ig
región variable de la inmunoglobulina
Scope note: Región de las moléculas de inmunoglobulinas que varía en su secuencia y composición de aminoácidos y comprende el sitio de unión para un antígeno específico. Se localiza en la posición N terminal del fragmento Fab de la inmunoglobulina. Incluye las regiones hipervariables (REGIONES DETERMINANTES DE COMPLEMENTARIEDAD) y las regiones armazón.
Descriptor Portuguese: Região Variável de Imunoglobulina
Descriptor French: Région variable d'immunoglobuline
Entry term(s): Immunoglobuline V
Région charpente d'Ig
Région charpente d'immunoglobuline
Région variable d'Ig
Région variable de l'immunoglobuline
Tree number(s): D12.644.541.500.650.500
D12.776.124.486.485.680.650.500
D12.776.124.486.485.797
D12.776.124.790.651.680.650.500
D12.776.124.790.651.797
D12.776.377.715.548.680.650.500
D12.776.377.715.548.797
G02.111.570.060.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007135
Scope note: That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
DE effets des médicaments et des substances chimiques
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PO intoxication
RE effets des radiations
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Related: Domaines immunoglobuline MeSH
Sites de fixation des anticorps MeSH
DeCS ID: 22209
Unique ID: D007135
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1976/04/16
Revision Date: 2015/11/20
Région variable d'immunoglobuline - Preferred
Concept UI M0011118
Preferred term Région variable d'immunoglobuline
Entry term(s) Immunoglobuline V
Région variable d'Ig
Région variable de l'immunoglobuline
Région charpente d'immunoglobuline - Narrower
Concept UI M0011116
Preferred term Région charpente d'immunoglobuline
Entry term(s) Région charpente d'Ig



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