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Descriptor English: Somatomedins
Descriptor Spanish: Somatomedinas
Descriptor somatomedinas
Entry term(s) factor de sulfatación
Scope note: Polipéptidos de tipo insulina fabricados por el hígado y algunos fibroblastos y liberados a la circulación sanguínea cuando son estimulados por la SOMATOTROPINA. Producen la incorporación de sulfato al colágeno, síntesis de ARN y de ADN, que son requisitos para la división celular y crecimiento del organismo.
Descriptor Portuguese: Somatomedinas
Descriptor French: Somatomédines
Entry term(s): Factor, Sulfation
Somatomedin
Sulfation Factor
Tree number(s): D12.644.276.742.500
D12.776.124.862
D12.776.467.742.500
D23.529.742.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013002
Scope note: Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Blood Proteins (1966-1970)
Sulfates/metabolism (1966-1970)
Public MeSH Note: 82; was SOMATOMEDIN 1973-81
Online Note: use SOMATOMEDINS to search SOMATOMEDIN 1973-81 & SULFATION FACTOR 1971-72 (as Prov 1971-72)
History Note: 82; was SOMATOMEDIN 1973-81, was SULFATION FACTOR 1971-72 (Prov)
Related: Receptors, Somatomedin MeSH
DeCS ID: 22294
Unique ID: D013002
NLM Classification: QU 107
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Somatomedins - Preferred
Concept UI M0020150
Scope note Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.
Preferred term Somatomedins
Entry term(s) Factor, Sulfation
Somatomedin
Sulfation Factor



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