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Descriptor English: Platelet-Derived Growth Factor
Descriptor Spanish: Factor de Crecimiento Derivado de Plaquetas
Descriptor factor de crecimiento derivado de plaquetas
Scope note: Hormona de crecimiento compuesta por un péptido mitogénico transportado en los gránulos alfa de las plaquetas. Se libera cuando las plaquetas se adhieren a los tejidos traumatizados. Las células del tejido conectivo cercanas a la región traumatizada responden iniciando el proceso de replicación.
Descriptor Portuguese: Fator de Crescimento Derivado de Plaquetas
Descriptor French: Facteur de croissance dérivé des plaquettes
Entry term(s): Factor, Platelet-Derived Growth
Growth Factor, Platelet-Derived
Platelet Derived Growth Factor
Tree number(s): D12.644.276.910
D12.776.124.625
D12.776.467.910
D23.529.910
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010982
Scope note: Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Blood Proteins (1977-1983)
Growth Substances (1977-1983)
Peptides (1977-1983)
Public MeSH Note: 84
History Note: 84
Entry Version: PDGF
Related: Receptors, Platelet-Derived Growth Factor MeSH
DeCS ID: 22257
Unique ID: D010982
NLM Classification: WH 300
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1983/05/31
Revision Date: 2006/07/05
Platelet-Derived Growth Factor - Preferred
Concept UI M0017024
Scope note Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
Preferred term Platelet-Derived Growth Factor
Entry term(s) Factor, Platelet-Derived Growth
Growth Factor, Platelet-Derived
Platelet Derived Growth Factor



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