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Descriptor English: beta 2-Glycoprotein I
Descriptor Spanish: beta 2 Glicoproteína I
Descriptor beta 2-glicoproteína I
Entry term(s) apolipoproteína H
Scope note: Proteína plasmática de 44 kDa muy glicosilada que se une a fosfolípidos que incluyen CARDIOLIPINA, RECEPTOR DE APOLIPOPROTEÍNA E, fosfolípidos membranarios y otros grupos que contienen fosfolípidos aniónicos. Desempeña un papel en la coagulación y procesos apoptósicos. Conocida antiguamente como apolipoproteína H, es un autoantígeno en pacientes con ANTICUERPOS ANTIFOSFOLÍPIDOS.
Descriptor Portuguese: beta 2-Glicoproteína I
Descriptor French: bêta 2-Glycoprotéine I
Entry term(s): Anticardiolipin Cofactor
Apo H
Apolipoprotein H
Cofactor, Anticardiolipin
EC VMFa
EC-VMFa
Endothelial Cell Viability Maintaining Factor
Endothelial Cell-Viability Maintaining Factor
beta 2 Glycoprotein I
beta(2)GPI
beta2 Glycoprotein I
beta2-Glycoprotein I
Tree number(s): D09.400.430.687
D12.776.124.117
D12.776.395.195
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053482
Scope note: A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Anticoagulants
Previous Indexing: Glycoproteins (1967-2006)
Public MeSH Note: 2007; was indexed under GLYCOPROTEINS 1979-2006
History Note: 2007; BETA 2-GLYCOPROTEIN I (NM) 1979-2006
DeCS ID: 52320
Unique ID: D053482
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
beta 2-Glycoprotein I - Preferred
Concept UI M0071001
Scope note A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.
Preferred term beta 2-Glycoprotein I
Entry term(s) Anticardiolipin Cofactor
Apo H
Apolipoprotein H
Cofactor, Anticardiolipin
EC VMFa
EC-VMFa
Endothelial Cell Viability Maintaining Factor
Endothelial Cell-Viability Maintaining Factor
beta 2 Glycoprotein I
beta(2)GPI
beta2 Glycoprotein I
beta2-Glycoprotein I



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