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Descriptor English: Cinnarizine
Descriptor Spanish: Cinarizina
Descriptor cinarizina
Scope note: Derivado de la piperazina que tiene actividad bloqueante de los receptores H1 de histamina y los canales del calcio, con propiedades antieméticas pero que induce TRASTORNOS PARKINSONIANOS.
Descriptor Portuguese: Cinarizina
Descriptor French: Cinnarizine
Entry term(s): Dichlorhydrate de cinnarizine
R-516
R516
Tree number(s): D03.383.606.290
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002936
Scope note: A piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Calcium Channel Blockers
Histamine H1 Antagonists
Registry Number: 3DI2E1X18L
CAS Type 1 Name: Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-
DeCS ID: 2963
Unique ID: D002936
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1974/11/19
Revision Date: 2017/05/24
Cinnarizine - Preferred
Concept UI M0004492
Preferred term Cinnarizine
Dichlorhydrate de cinnarizine - Narrower
Concept UI M0331355
Preferred term Dichlorhydrate de cinnarizine
R-516 - Narrower
Concept UI M0353364
Preferred term R-516
Entry term(s) R516



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