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Descriptor English: Hydroxyzine
Descriptor Spanish: Hidroxizina
Descriptor hidroxicina
Scope note: Antagonista de los receptores H1 de histamina que es efectivo en el tratamiento de la urticaria crónica, dermatítis y prurito mediado por histamina. A diferencia de su metabolito CETIRICINA, este compuesto causa somnolencia. Asimismo, es efectivo como antiemético, como ansiolítico y relajante, y como sedante.
Descriptor Portuguese: Hidroxizina
Descriptor French: Hydroxyzine
Entry term(s): 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol
Atarax
Durrax
Hydroxyzine Dihydrochloride
Hydroxyzine Hydrochloride
Hydroxyzine Pamoate
Orgatrax
Pamoate, Hydroxyzine
Vistaril
Tree number(s): D03.383.606.515
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006919
Scope note: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antipruritics
Histamine H1 Antagonists
Registry Number: 30S50YM8OG
CAS Type 1 Name: Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-
DeCS ID: 7098
Unique ID: D006919
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Hydroxyzine - Preferred
Concept UI M0010792
Scope note A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Preferred term Hydroxyzine
Entry term(s) 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol
Hydroxyzine Dihydrochloride - Narrower
Concept UI M0331417
Preferred term Hydroxyzine Dihydrochloride
Vistaril - Narrower
Concept UI M0010794
Preferred term Vistaril
Hydroxyzine Pamoate - Narrower
Concept UI M0331416
Preferred term Hydroxyzine Pamoate
Entry term(s) Pamoate, Hydroxyzine
Orgatrax - Narrower
Concept UI M0010793
Preferred term Orgatrax
Durrax - Narrower
Concept UI M0372532
Preferred term Durrax
Atarax - Narrower
Concept UI M0010796
Preferred term Atarax
Hydroxyzine Hydrochloride - Narrower
Concept UI M0010795
Preferred term Hydroxyzine Hydrochloride



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