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Descriptor English: Ketoconazole
Descriptor Spanish: Cetoconazol
Descriptor Portuguese: Cetoconazol
Descriptor French: Kétoconazole
Entry term(s): Nizoral
R 41400
R-41400
R41,400
R41400
Tree number(s): D03.383.606.560
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007654
Scope note: Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antifungal Agents
14-alpha Demethylase Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number: R9400W927I
CAS Type 1 Name: Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis-
Previous Indexing: Imidazoles (1966-1983)
Piperazines (1966-1983)
Public MeSH Note: 84
History Note: 84
DeCS ID: 7819
Unique ID: D007654
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1983/03/11
Revision Date: 2017/05/24
Ketoconazole - Preferred
Concept UI M0011987
Scope note Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
Preferred term Ketoconazole
R-41400 - Narrower
Concept UI M0353370
Preferred term R-41400
Entry term(s) R 41400
R41,400
R41400
Nizoral - Narrower
Concept UI M0011988
Preferred term Nizoral



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