| Descriptor English: | Vortioxetine | ||||||
| Descriptor Spanish: |
Vortioxetina
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| Descriptor Portuguese: | Vortioxetina | ||||||
| Descriptor French: | Vortioxétine | ||||||
| Entry term(s): |
1-(2-(2,4-Dimethylphenylsulfanyl)phenyl)piperazine Brintellix Lu AA21004 Lu-AA21004 LuAA21004 Vortioxetine Hydrobromide |
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| Tree number(s): |
D03.383.606.990 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000078784 | ||||||
| Scope note: | A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Antidepressive Agents Antidepresivos Antidepressivos Antidépresseurs antidepresivos Anti-Anxiety Agents Ansiolíticos Ansiolíticos Anxiolytiques ansiolíticos Serotonin Uptake Inhibitors Inhibidores Selectivos de la Recaptación de Serotonina inhibidores selectivos de la recaptación de serotonina Inbiteurs sélectifs de la recapture de la sérotonine Inibidores Seletivos de Recaptação de Serotonina Serotonin 5-HT1 Receptor Agonists Agonistas del Receptor de Serotonina 5-HT1 Agonistas do Receptor 5-HT1 de Serotonina Agonistes des récepteurs 5-HT1 de la sérotonine agonistas de receptores de serotonina 5-HT1 Serotonin 5-HT3 Receptor Antagonists Antagonistas del Receptor de Serotonina 5-HT3 Antagonistas do Receptor 5-HT3 de Serotonina Antagonistes des récepteurs 5-HT3 de la sérotonine antagonistas de receptores de serotonina 5-HT3 |
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| Registry Number: | 3O2K1S3WQV | ||||||
| Public MeSH Note: | 2019; VORTIOXETINE was indexed under PIPERAZINES and SULFIDES 2011-2018 |
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| History Note: | 2019 (2011) |
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| DeCS ID: | 57854 | ||||||
| Unique ID: | D000078784 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2019/01/01 | ||||||
| Date of Entry: | 2018/07/09 | ||||||
| Revision Date: | 2018/07/03 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
|
|
Vortioxetine
- Preferred
Lu AA21004
- Narrower
Brintellix
- Narrower
Vortioxetine Hydrobromide
- Narrower
| Concept UI |
M0586839 |
| Scope note | A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression. |
| Preferred term | Vortioxetine |
| Entry term(s) |
1-(2-(2,4-Dimethylphenylsulfanyl)phenyl)piperazine |
| Concept UI |
M0557313 |
| Preferred term | Lu AA21004 |
| Entry term(s) |
Lu-AA21004 LuAA21004 |
| Concept UI |
M000638093 |
| Preferred term | Brintellix |
| Concept UI |
M0588225 |
| Preferred term | Vortioxetine Hydrobromide |
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