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Descriptor English: Vortioxetine
Descriptor Spanish: Vortioxetina
Descriptor vortioxetina
Entry term(s) 1-(2-(2,4-dimetilfenilsulfanil)fenil)piperazina
Lu AA21004
Lu-AA21004
LuAA21004
brintellix
hidrobromuro de vortioxetina
Scope note: Derivado piperacínico que actúa como inhibidor de la recaptación de serotonina, como antagonista de los receptores 5-HT3 y como agonista de los receptores 5-HT1A. Se usa para el tratamiento de la ansiedad y de la depresión.
Descriptor Portuguese: Vortioxetina
Descriptor French: Vortioxétine
Entry term(s): 1-(2-(2,4-Dimethylphenylsulfanyl)phenyl)piperazine
Brintellix
Lu AA21004
Lu-AA21004
LuAA21004
Vortioxetine Hydrobromide
Tree number(s): D03.383.606.990
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078784
Scope note: A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents
Anti-Anxiety Agents
Serotonin Uptake Inhibitors
Serotonin 5-HT1 Receptor Agonists
Serotonin 5-HT3 Receptor Antagonists
Registry Number: 3O2K1S3WQV
Public MeSH Note: 2019; VORTIOXETINE was indexed under PIPERAZINES and SULFIDES 2011-2018
History Note: 2019 (2011)
DeCS ID: 57854
Unique ID: D000078784
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03
Vortioxetine - Preferred
Concept UI M0586839
Scope note A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.
Preferred term Vortioxetine
Entry term(s) 1-(2-(2,4-Dimethylphenylsulfanyl)phenyl)piperazine
Lu AA21004 - Narrower
Concept UI M0557313
Preferred term Lu AA21004
Entry term(s) Lu-AA21004
LuAA21004
Brintellix - Narrower
Concept UI M000638093
Preferred term Brintellix
Vortioxetine Hydrobromide - Narrower
Concept UI M0588225
Preferred term Vortioxetine Hydrobromide



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