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Descriptor English: Diazepam Binding Inhibitor
Descriptor Spanish: Inhibidor de la Unión a Diazepam
Descriptor inhibidor de la unión a diacepam
Entry term(s) proteína de unión al acil-CoA
Scope note: Polipéptido de 86 aminoácidos que se encuentra en los tejidos centrales y periféricos, que desplaza al diacepam del sitio de reconocimiento de las benzodiacepinas en el receptor del ácido gamma-amionobutírico (RECEPTORES, GABA). Se une también a los ésteres de acil-CoA de cadena media y larga y hace la función de transportador de acil-CoA. Este péptido regula el metabolismo de los lípidos.
Descriptor Portuguese: Inibidor da Ligação a Diazepam
Descriptor French: Inhibiteur de la liaison au diazépam
Entry term(s): Acyl CoA Binding Protein
Acyl-CoA-Binding Protein
Binding Inhibitor, Diazepam
DBI Peptide
Endozepine
EpDBI
Inhibitor, Diazepam Binding
Medium Chain Acyl CoA Binding Protein
Medium-Chain Acyl CoA-Binding Protein
Peptide, DBI
Protein, Acyl-CoA-Binding
Tree number(s): D12.644.136
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D026261
Scope note: An 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (RECEPTORS, GABA). It also binds medium- and long-chain acyl-CoA esters and serves as an acyl-CoA transporter. This peptide regulates lipid metabolism.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Carrier Proteins (1992-2001)
Nerve Tissue Proteins (1984-1986)
Neuropeptides (1987-1992)
Public MeSH Note: 2002; DIAZEPAM BINDING INHIBITOR was indexed under CARRIER PROTEINS 1984-2001
History Note: 2002; use DIAZEPAM BINDING INHIBITOR (NM) 1984-2001
DeCS ID: 36132
Unique ID: D026261
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2011/06/24
Diazepam Binding Inhibitor - Preferred
Concept UI M0121114
Scope note An 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (RECEPTORS, GABA). It also binds medium- and long-chain acyl-CoA esters and serves as an acyl-CoA transporter. This peptide regulates lipid metabolism.
Preferred term Diazepam Binding Inhibitor
Entry term(s) Acyl CoA Binding Protein
Acyl-CoA-Binding Protein
Binding Inhibitor, Diazepam
DBI Peptide
Endozepine
EpDBI
Inhibitor, Diazepam Binding
Peptide, DBI
Protein, Acyl-CoA-Binding
Medium-Chain Acyl CoA-Binding Protein - Narrower
Concept UI M0377491
Preferred term Medium-Chain Acyl CoA-Binding Protein
Entry term(s) Medium Chain Acyl CoA Binding Protein



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