| Descriptor English: | Trefoil Factors | ||||||
| Descriptor Spanish: |
Factores Trefoil
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| Descriptor Portuguese: | Fatores Trefoil | ||||||
| Descriptor French: | Facteurs en trèfle | ||||||
| Entry term(s): |
Factor, Trefoil Peptide, TFF Peptide, Trefoil Protein, Trefoil TFF Peptide TFF Peptides Trefoil Factor Trefoil Factor Family Peptides Trefoil Factor Family Proteins Trefoil Peptide Trefoil Peptides Trefoil Protein Trefoil Proteins |
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| Tree number(s): |
D12.644.937 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071162 | ||||||
| Scope note: | A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Previous Indexing: |
Mucins (1992-2016) Peptides (1992-2016) |
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| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56552 | ||||||
| Unique ID: | D000071162 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Trefoil Factors
- Preferred
| Concept UI |
M000613336 |
| Scope note | A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents. |
| Preferred term | Trefoil Factors |
| Entry term(s) |
Factor, Trefoil Peptide, TFF Peptide, Trefoil Protein, Trefoil TFF Peptide TFF Peptides Trefoil Factor Trefoil Factor Family Peptides Trefoil Factor Family Proteins Trefoil Peptide Trefoil Peptides Trefoil Protein Trefoil Proteins |
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