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Descriptor in English: Cystine-Knot Miniproteins
Descriptor in Spanish: Miniproteínas Nodales de Cistina
Descriptor in Portuguese: Miniproteínas Nó de Cistina
Descriptor in French: Miniprotéines à noeud de cystine
Entry term(s): Cystine Knot Miniproteins
Knottin
Knottins
Tree number(s): D12.644.132
D12.776.217
Scope note: A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2011
DeCS UI: 54054
Descriptor UI: D057771
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Cystine-Knot Miniproteins - Preferred
Concept UI M0539010
Scope note A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins.
Preferred term Cystine-Knot Miniproteins
Entry term(s) Cystine Knot Miniproteins
Knottin
Knottins



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