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Descriptor English: Ephrin-A1
Descriptor Spanish: Efrina-A1
Descriptor efrina A1
Entry term(s) EFNA1
EPLG1
ligando de Eck
ligando del RPTK Eck
proteína B61 secretada por el endotelio
proteína B61 segregada por el endotelio
proteína Epl1
proteína LERK-1
Scope note: Efrina identificada originalmente como el producto de un gen de respuesta temprana inducido por los FACTORES DE NECROSIS TUMORAL. Está unida a la MEMBRANA CELULAR por un ANCLA MEMBRANARIA DE GLICOINOSITOL FOSFOLÍPIDO y se une al RECEPTOR EPHA2 con una gran afinidad. Durante la embriogénesis se expresan unas concentraciones elevadas de efrina A1 en el PULMÓN, RIÑÓN, GLÁNDULAS SALIVALES e INTESTINO.
Descriptor Portuguese: Efrina-A1
Descriptor French: Éphrine A1
Entry term(s): B61 Secreted Protein, Endothelium
EFNA1
EPLG1
Eck Ligand
Eck RPTK Ligand
Endothelium Secreted Protein B61
Ephrin A1
Epl1 Protein
LERK 1 Protein
LERK-1 Protein
Ligand, Eck
RPTK Ligand, Eck
Tree number(s): D09.400.430.890.448.300
D12.644.276.500.100
D12.776.395.550.448.300
D12.776.467.500.100
D12.776.543.287.100
D12.776.543.484.500.300
D12.776.543.550.418.300
D23.529.500.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D036382
Scope note: An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Proteins (1990-2002)
Public MeSH Note: 2003; ENDOTHELIUM SECRETED PROTEIN B61 (now Ephrin-A1) was indexed under PROTEINS 1990-2002,
History Note: 2003; use EPHRIN-A1 (NM) 1990-2002
DeCS ID: 37366
Unique ID: D036382
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2010/06/25
Ephrin-A1 - Preferred
Concept UI M0181712
Scope note An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
Preferred term Ephrin-A1
Entry term(s) B61 Secreted Protein, Endothelium
EFNA1
EPLG1
Eck Ligand
Eck RPTK Ligand
Endothelium Secreted Protein B61
Ephrin A1
Epl1 Protein
LERK 1 Protein
LERK-1 Protein
Ligand, Eck
RPTK Ligand, Eck



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