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Descriptor English: Glial Cell Line-Derived Neurotrophic Factor Receptors
Descriptor Spanish: Receptores del Factor Neurotrófico Derivado de la Línea Celular Glial
Descriptor receptores de factores neurotróficos derivados de células gliales
Entry term(s) receptores de factores neurotróficos derivados de la línea celular glial
Scope note: Familia de receptores del GLICOSILFOSFATIDILINOSITOL ubicados en la superficie de la célula, específicos de los FACTORES NEUROTRÓFICOS DERIVADOS DE LA LÍNEA CELULAR GLIAL. Forman un complejo receptor de varios componentes con la PROTEÍNA PROTOONCOGÉNICA C-RET y regula diversas VÍAS DE TRANSDUCCIÓN DE SEÑALES conjuntamente con la proteína c-ret.
Descriptor Portuguese: Receptores de Fator Neurotrófico Derivado de Linhagem de Célula Glial
Descriptor French: Récepteurs des facteurs neurotrophiques dérivés des cellules gliales
Entry term(s): GDNF Family Receptor 1
GDNF Family Receptor 2
GDNF Family Receptor 3
GDNF Family Receptor 4
GDNF Family Receptor Alpha 1
GDNF Family Receptor Alpha 2
GDNF Family Receptor Alpha 3
GDNF Family Receptor Alpha 4
GDNF Receptors
GFRA1 Receptor
GFRA2 Receptor
GFRA3 Receptor
GFRA4 Receptor
Glial Cell Line Derived Neurotrophic Factor Receptors
Glial Derived Neurotrophic Factor Receptor 1
Glial Derived Neurotrophic Factor Receptor 2
Glial Derived Neurotrophic Factor Receptor 3
Glial Derived Neurotrophic Factor Receptor 4
Tree number(s): D09.400.430.890.448.400
D12.776.395.550.448.400
D12.776.543.484.500.400
D12.776.543.550.418.400
D12.776.543.750.750.400.550.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051097
Scope note: A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored cell surface receptors that are specific for GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS. They form a multi-component receptor complex with PROTO-ONCOGENE PROTEIN C-RET and regulate a variety of intracellular SIGNAL TRANSDUCTION PATHWAYS in conjunction with c-ret protein.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR RECEPTORS was indexed under PROTO-ONCOGENE PROTEINS & RECEPTOR PROTEIN-TYROSINE KINASES 1999-2005
History Note: 2006(1999)
DeCS ID: 51152
Unique ID: D051097
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2010/06/25
Glial Cell Line-Derived Neurotrophic Factor Receptors - Preferred
Concept UI M0166928
Scope note A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored cell surface receptors that are specific for GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS. They form a multi-component receptor complex with PROTO-ONCOGENE PROTEIN C-RET and regulate a variety of intracellular SIGNAL TRANSDUCTION PATHWAYS in conjunction with c-ret protein.
Preferred term Glial Cell Line-Derived Neurotrophic Factor Receptors
Entry term(s) GDNF Receptors
Glial Cell Line Derived Neurotrophic Factor Receptors
GFRA4 Receptor - Narrower
Concept UI M0479210
Preferred term GFRA4 Receptor
Entry term(s) GDNF Family Receptor 4
GDNF Family Receptor Alpha 4
Glial Derived Neurotrophic Factor Receptor 4
GFRA3 Receptor - Narrower
Concept UI M0479209
Preferred term GFRA3 Receptor
Entry term(s) GDNF Family Receptor 3
GDNF Family Receptor Alpha 3
Glial Derived Neurotrophic Factor Receptor 3
GFRA1 Receptor - Narrower
Concept UI M0479207
Preferred term GFRA1 Receptor
Entry term(s) GDNF Family Receptor 1
GDNF Family Receptor Alpha 1
Glial Derived Neurotrophic Factor Receptor 1
GFRA2 Receptor - Narrower
Concept UI M0479208
Preferred term GFRA2 Receptor
Entry term(s) GDNF Family Receptor 2
GDNF Family Receptor Alpha 2
Glial Derived Neurotrophic Factor Receptor 2



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